Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 4/20 | 0.78 |
| ▸ | PGK2 | P07205 | 4/20 | 0.78 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.65 |
| ▸ | PTPN5 | P54829 | 7/20 | 0.62 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.58 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.58 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14029155 | 0.87 | PGK1 (0.58) | PGK1PGK2PTPN1PTPN5PTPN2 | |
| SCHEMBL14076365 | 0.83 | PGK1 (0.78) | PGK1PGK2PTPN1PTPN5PTPN2 | |
| SCHEMBL6428108 | 0.79 | PTPN1 (1.00) | PGK1PGK2PTPN1PTPN5PTPN2 | |
| SCHEMBL3892973 | 0.79 | PGK1 (0.48) | PGK1PGK2PTPN1PTPN5 | |
| SCHEMBL6838700 | 0.78 | PGK1 (0.78) | PGK1PGK2PTPN1PTPN5PTPN2 | |
| SCHEMBL2637465 | 0.78 | PGK1 (0.78) | PGK1PGK2PTPN1PTPN5PTPN2 | |
| SCHEMBL5499239 | 0.78 | PGK1 (0.78) | PGK1PGK2PTPN1PTPN5PTPN2 | |
| SCHEMBL14029162 | 0.76 | TSHR (0.48) | PGK1PGK2PTPN5 | |
| SCHEMBL11759829 | 0.76 | TSHR (0.48) | PGK1PGK2PTPN1PTPN5PTPN2 | |
| SCHEMBL10684331 | 0.76 | TSHR (0.48) | PGK1PGK2PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | PTPRS, PTPRJ, PTPRCAP | PGK1 1860/4885PGK2 1206/4885PTPN1 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.