Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.64 |
| ▸ | MAOB | P27338 | 13/20 | 0.60 |
| ▸ | MAOA | P21397 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.57 |
| ▸ | RELA | Q04206 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23189125 | 0.84 | MAOB (0.82) | MRGPRX4MAOBMAOATP53PKM | |
| SCHEMBL21483709 | 0.81 | MAOB (0.72) | MRGPRX4MAOBMAOATP53PKM | |
| SCHEMBL27385121 | 0.81 | MRGPRX4 (0.68) | MRGPRX4MAOBMAOATP53PKM | |
| SCHEMBL13813140 | 0.81 | MAOB (0.63) | MRGPRX4MAOBMAOATP53PKM | |
| SCHEMBL22480782 | 0.80 | MRGPRX4 (0.76) | MRGPRX4MAOBMAOATP53PKM | |
| SCHEMBL6157345 | 0.80 | MAOB (0.43) | MAOBMAOA | |
| SCHEMBL6960292 | 0.78 | MRGPRX4 (0.72) | MRGPRX4MAOBMAOATP53PKM | |
| SCHEMBL21234292 | 0.78 | MRGPRX4 (1.00) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL6155391 | 0.77 | MAOB (0.62) | MRGPRX4MAOBMAOATP53PKM | |
| SCHEMBL6155843 | 0.76 | MRGPRX4 (0.46) | MRGPRX4MAOBTP53PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |