Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3283557 | 0.85 | LTB4R (0.41) | LTB4RCYP4F2CYP4A11MAPTALDH1A1 | |
| SCHEMBL9660695 | 0.83 | MAOB (0.58) | MAOBKMT2ACYP4F2CYP4A11MEN1 | |
| SCHEMBL6884477 | 0.80 | KMT2A (0.55) | KMT2AMEN1TAAR1LMNAMAPT | |
| SCHEMBL6155402 | 0.80 | MRGPRX4 (0.64) | MAOBMAOA | |
| SCHEMBL8341269 | 0.77 | CYP4F2 (0.53) | MAOBKMT2ACYP4F2CYP4A11MEN1 | |
| SCHEMBL4958280 | 0.76 | KAT6A (0.51) | MAOBCYP4F2CYP4A11LMNAMAOA | |
| SCHEMBL12235066 | 0.76 | CYP4F2 (0.67) | MAOBCYP4F2CYP4A11LMNAMAOA | |
| SCHEMBL6157330 | 0.76 | VDR (0.50) | MAOBCYP4F2CYP4A11LMNAMAOA | |
| SCHEMBL10442102 | 0.76 | ALDH1A1 (0.47) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL6158543 | 0.76 | PPARA (0.47) | MAOBKMT2AMEN1MAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |