Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156157 | 0.85 | HMGCR (0.48) | CYP4F2CYP4A11HDAC4AKR1B10AKR1B1 | |
| SCHEMBL4850556 | 0.75 | MAPT (0.50) | MAPTRXFP1PPARAHDAC3MAPK1 | |
| SCHEMBL6155454 | 0.74 | MAPT (0.40) | MAPTRXFP1ALOX5PPARACYP4F2 | |
| SCHEMBL6155458 | 0.74 | MAPT (0.40) | MAPTRXFP1ALOX5PPARACYP4F2 | |
| SCHEMBL7775456 | 0.71 | FFAR1 (0.44) | MAPTRXFP1 | |
| SCHEMBL6156494 | 0.71 | FFAR1 (0.48) | PPARAPPARGCYSLTR2CYSLTR1AKR1B1 | |
| SCHEMBL13491997 | 0.70 | HDAC4 (0.59) | MAPTRXFP1CYP4F2CYP4A11HDAC3 | |
| SCHEMBL6156488 | 0.70 | PPARA (0.47) | MAPTRXFP1ALOX5PPARASMN1; SMN2 | |
| SCHEMBL6156496 | 0.70 | PPARA (0.47) | MAPTRXFP1ALOX5PPARASMN1; SMN2 | |
| SCHEMBL6155173 | 0.69 | PPARA (0.48) | MAPTRXFP1ALOX5PPARAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |