Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158473 | 0.86 | CYP4F2 (0.38) | FFAR1PPARAPPARG | |
| SCHEMBL6155413 | 0.79 | CYSLTR2 (0.47) | FFAR1CYSLTR2CYSLTR1FFAR4AKR1B1 | |
| SCHEMBL7775456 | 0.79 | FFAR1 (0.44) | FFAR1FFAR4 | |
| SCHEMBL6155257 | 0.75 | MAOB (0.52) | — | |
| SCHEMBL4847215 | 0.74 | CYSLTR2 (0.69) | FFAR1CYSLTR2CYSLTR1FFAR4PPARA | |
| SCHEMBL4392789 | 0.74 | FFAR1 (0.64) | FFAR1CYSLTR2CYSLTR1FFAR4AKR1B1 | |
| SCHEMBL5763262 | 0.73 | FFAR1 (0.70) | FFAR1CYSLTR2CYSLTR1FFAR4PPARA | |
| SCHEMBL6156487 | 0.72 | CYSLTR2 (0.50) | FFAR1CYSLTR2CYSLTR1FFAR4PPARA | |
| SCHEMBL959881 | 0.72 | CYSLTR2 (0.58) | FFAR1CYSLTR2CYSLTR1FFAR4PPARA | |
| SCHEMBL6885404 | 0.71 | CYSLTR2 (0.48) | FFAR1CYSLTR2CYSLTR1FFAR4PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |