Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155454 | 1.00 | MAPT (0.40) | MAPTRXFP1CYSLTR2CYSLTR1TBXAS1 | |
| SCHEMBL6885100 | 0.90 | CYP4F2 (0.44) | AKR1B10AKR1B1ALOX5CYP4F2CYP4A11 | |
| SCHEMBL6156155 | 0.85 | HMGCR (0.49) | AKR1B10AKR1B1CYP4F2CYP4A11HDAC4 | |
| SCHEMBL20298754 | 0.78 | LCK (0.44) | MAPTPPARASMN1; SMN2BACE1 | |
| SCHEMBL8891538 | 0.74 | APP (0.51) | ALOX5HDAC4BACE1 | |
| SCHEMBL8891530 | 0.74 | APP (0.51) | ALOX5HDAC4BACE1 | |
| SCHEMBL6155460 | 0.74 | MAPT (0.39) | MAPTRXFP1CYSLTR2CYSLTR1TBXAS1 | |
| SCHEMBL6156487 | 0.73 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1PPARACYP4F2CYP4A11 | |
| SCHEMBL6885569 | 0.73 | FFAR1 (0.46) | MAPTRXFP1TBXAS1 | |
| SCHEMBL4848823 | 0.73 | MAPT (0.50) | MAPTRXFP1CYSLTR2CYSLTR1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |