Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SPR | P35270 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154283 | 0.86 | KMT2A (0.53) | KMT2ASMN1; SMN2MAPTLMNAPDE4B | |
| SCHEMBL6156758 | 0.82 | KDM4E (0.41) | SPRSMN1; SMN2GAALMNAALDH1A1 | |
| SCHEMBL6155240 | 0.82 | MAPK1 (0.45) | KMT2ASMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL841372 | 0.82 | LMNA (0.54) | KMT2ASPRSMN1; SMN2GAAMAPT | |
| SCHEMBL773597 | 0.82 | MAPK14 (0.38) | KMT2AGAALMNAPDE4BALDH1A1 | |
| SCHEMBL6155187 | 0.81 | TSHR (0.40) | SMN1; SMN2LMNAALDH1A1RAB9ACYP1A2 | |
| SCHEMBL6156185 | 0.81 | LMNA (0.37) | KMT2ASMN1; SMN2LMNAPDE4BALDH1A1 | |
| SCHEMBL4715135 | 0.77 | KMT2A (0.45) | KMT2ASPRSMN1; SMN2LMNAPDE4B | |
| SCHEMBL6156766 | 0.77 | KMT2A (0.45) | KMT2ASPRSMN1; SMN2GAAMAPT | |
| SCHEMBL6155638 | 0.77 | KMT2A (0.45) | KMT2ASPRSMN1; SMN2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1580189-A1 | 4-AMINO-5-METHYLPYRAZOLE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | Sankyo Agro Company, Limited (JP) | 2005-09-28 | — | — | EP | disclosed |