Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17438055 | 0.87 | KMT2A (0.52) | KMT2ASMN1; SMN2NPC1LMNAHPGD | |
| SCHEMBL6155564 | 0.86 | KMT2A (0.46) | KMT2ASMN1; SMN2NPC1LMNAPDE4B | |
| SCHEMBL31352277 | 0.85 | NPC1 (0.62) | KMT2ASMN1; SMN2NPC1LMNAHPGD | |
| SCHEMBL13462878 | 0.84 | SMN1; SMN2 (0.58) | KMT2ASMN1; SMN2NPC1LMNAPDE4B | |
| SCHEMBL6664950 | 0.83 | SMN1; SMN2 (0.56) | KMT2ASMN1; SMN2NPC1LMNAHPGD | |
| SCHEMBL2088511 | 0.82 | KDM4E (0.47) | KMT2ASMN1; SMN2NPC1LMNAPDE4B | |
| SCHEMBL6155240 | 0.81 | MAPK1 (0.45) | KMT2ASMN1; SMN2LMNAHPGDRAB9A | |
| SCHEMBL6156758 | 0.81 | KDM4E (0.41) | SMN1; SMN2LMNARAB9AKDM4EALDH1A1 | |
| SCHEMBL3509334 | 0.80 | SMN1; SMN2 (0.54) | KMT2ASMN1; SMN2NPC1LMNAPDE4B | |
| SCHEMBL6156185 | 0.80 | LMNA (0.37) | KMT2ASMN1; SMN2NPC1LMNAPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1580189-A1 | 4-AMINO-5-METHYLPYRAZOLE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | Sankyo Agro Company, Limited (JP) | 2005-09-28 | — | — | EP | disclosed |