Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155603 | 0.87 | FFAR1 (0.39) | CYSLTR2CYSLTR1FFAR1BCHE | |
| SCHEMBL2106818 | 0.79 | CYSLTR2 (0.42) | CYSLTR2CYSLTR1FFAR1BCHEMEN1 | |
| SCHEMBL6155587 | 0.77 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1FFAR1BCHEMEN1 | |
| SCHEMBL6155571 | 0.74 | VDR (0.46) | CYSLTR2CYSLTR1FFAR1BCHEALOX5 | |
| SCHEMBL6155248 | 0.74 | CYSLTR2 (0.42) | CYSLTR2CYSLTR1FFAR1BCHEMEN1 | |
| SCHEMBL2109172 | 0.73 | VDR (0.41) | CYSLTR2CYSLTR1FFAR1BCHE | |
| SCHEMBL2107789 | 0.73 | MRGPRX4 (0.44) | CYSLTR2CYSLTR1FFAR1BCHEALOX5 | |
| SCHEMBL6156678 | 0.72 | HMGCR (0.45) | KDM4ESMN1; SMN2 | |
| SCHEMBL6156685 | 0.72 | HMGCR (0.45) | KDM4ESMN1; SMN2 | |
| SCHEMBL6155242 | 0.72 | VDR (0.44) | CYSLTR2CYSLTR1FFAR1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |