SCHEMBL2106818

SCHEMBL2106818

CC(CCCC(C)(C)O)c1cccc(OCc2cc(O)cc(CO)c2)c1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 2/20 0.42
CYSLTR1 Q9Y271 2/20 0.42
BCHE P06276 1/20 0.37
FFAR1 O14842 1/20 0.36
ALOX5 P09917 1/20 0.35
SPHK1 Q9NYA1 1/20 0.35
APP P05067 1/20 0.35
KMT2A Q03164 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2109172 0.84 VDR (0.41) CYSLTR2CYSLTR1BCHEFFAR1SPHK1
SCHEMBL6155571 0.83 VDR (0.46) CYSLTR2CYSLTR1BCHEFFAR1ALOX5
SCHEMBL6155587 0.82 CYSLTR2 (0.44) CYSLTR2CYSLTR1BCHEFFAR1ALOX5
SCHEMBL6155242 0.81 VDR (0.44) CYSLTR2CYSLTR1BCHEFFAR1SPHK1
SCHEMBL6155601 0.79 CYSLTR2 (0.39) CYSLTR2CYSLTR1BCHEFFAR1ALOX5
SCHEMBL6155248 0.79 CYSLTR2 (0.42) CYSLTR2CYSLTR1BCHEFFAR1ALOX5
SCHEMBL2107787 0.79 VDR (0.40) CYSLTR2CYSLTR1BCHEFFAR1
SCHEMBL6155474 0.75 CYSLTR2 (0.45) CYSLTR2CYSLTR1FFAR1ALOX5KMT2A
SCHEMBL2107789 0.75 MRGPRX4 (0.44) CYSLTR2CYSLTR1BCHEFFAR1ALOX5
SCHEMBL6156188 0.75 ADRB1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1282636-C Vitamin D analogues GALDERMA RES & DEV (FR) 2006-11-01 CN claimed
EP-1124779-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2005-02-02 EP claimed
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 US claimed
CN-1332711-A Vitamin D analogues GALDERMA RES & DEV (FR) 2002-01-23 CN claimed
EP-2879656-B2 DYE COMPOSITION IN CREAM FORM COMPRISING AT LEAST ONE OIL AND LITTLE OR NO SOLID FATTY ALCOHOL, DYEING PROCESS AND SUITABLE DEVICE OREAL (FR) 2024-07-17 EP disclosed
US-11730682-B2 Self-standing cosmetic sheet L'OREAL (FR) 2023-08-22 US disclosed
EP-2836187-B1 SELF-STANDING COSMETIC SHEET OREAL (FR) 2021-12-08 EP disclosed
EP-2879656-B1 DYE COMPOSITION IN CREAM FORM COMPRISING AT LEAST ONE OIL AND LITTLE OR NO SOLID FATTY ALCOHOL, DYEING PROCESS AND SUITABLE DEVICE OREAL (FR) 2019-05-29 EP disclosed
US-10226411-B2 Dyeing composition comprising a fatty substance, a non-ionic guar gum, an amphoteric surfactant and a non-ionic or anionic surfactant, and an oxidizing agent, dyeing process and suitable device L'OREAL (FR) 2019-03-12 US disclosed
US-10201483-B2 Dye composition in cream form comprising at least one oil and little or no solid fatty alcohol, dyeing process and suitable device L'OREAL (FR) 2019-02-12 US disclosed
EP-2879649-B1 DYEING COMPOSITION COMPRISING AT LEAST ONE FATTY SUBSTANCE, AT LEAST ONE OXIDIZING AGENT AND AT LEAST ONE NON-IONIC, ANIONIC AND AMPHOTERIC SURFACTANT OREAL (FR) 2018-11-07 EP disclosed
US-20180235849-A1 SELF-STANDING COSMETIC SHEET L'OREAL (FR) 2018-08-23 US disclosed
EP-1559398-A1 Process for preparing a composition for the cosmetic treatment of keratinous materials on the basis of a pressurised fluid and vitamins L'OREAL (FR) 2005-08-03 EP disclosed
EP-1124779-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2005-02-02 EP disclosed
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 US disclosed
US-20020197289-A1 Compositions and methods for combating the appearance of ageing L'OREAL (FR) 2002-12-26 US disclosed
EP-1262168-A1 Composition containing fibres to combat the skin aging process L'OREAL (FR) 2002-12-04 EP disclosed
CN-1332711-A Vitamin D analogues GALDERMA RES & DEV (FR) 2002-01-23 CN disclosed
EP-1124779-A1 VITAMIN D ANALOGUES Galderma Research & Development, S.N.C. (FR) 2001-08-22 EP disclosed
WO-2000026167-A1 VITAMIN D ANALOGUES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2000-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10226411-B2 Dyeing composition comprising a fatty substance, a non-ionic guar gum, an amphoteric surfactant and a non-ionic or anionic surfactant, and an oxidizing agent, dyeing process and suitable device KRT18, OAT, DSG1 CYSLTR2 2051/4885CYSLTR1 1868/4885BCHE 2477/4885
US-20020197289-A1 Compositions and methods for combating the appearance of ageing CYP24A1, CYP27B1, CYP2R1 CYSLTR2 4433/4885CYSLTR1 4236/4885BCHE 569/4885
US-10201483-B2 Dye composition in cream form comprising at least one oil and little or no solid fatty alcohol, dyeing process and suitable device KRT18, CUTA, DSG1 CYSLTR2 1935/4885CYSLTR1 1818/4885BCHE 3171/4885
US-20180235849-A1 SELF-STANDING COSMETIC SHEET CUTA, DSG1, SUCLG1 CYSLTR2 2427/4885CYSLTR1 2592/4885BCHE 1497/4885
US-11730682-B2 Self-standing cosmetic sheet CUTA, DSG1, SUCLG1 CYSLTR2 2427/4885CYSLTR1 2592/4885BCHE 1497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.