Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 19/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155781 | 1.00 | MRGPRX4 (0.47) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL6881304 | 0.89 | MRGPRX4 (0.46) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL6881311 | 0.89 | MRGPRX4 (0.46) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL6562874 | 0.87 | CYP4F2 (0.34) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL6562882 | 0.87 | CYP4F2 (0.34) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL6155184 | 0.83 | VDR (0.48) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL6155188 | 0.83 | VDR (0.48) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL6155176 | 0.83 | VDR (0.48) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL6155547 | 0.83 | VDR (0.50) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL6155539 | 0.83 | VDR (0.50) | MRGPRX4TP53PKMNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |