Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886943 | 0.89 | NPC1 (0.35) | CYP4F2CYP4A11MAOBMRGPRX4SMN1; SMN2 | |
| SCHEMBL6886939 | 0.89 | NPC1 (0.35) | CYP4F2CYP4A11MAOBMRGPRX4SMN1; SMN2 | |
| SCHEMBL6564879 | 0.87 | MRGPRX4 (0.34) | CYP4F2CYP4A11MAOBMRGPRX4SMN1; SMN2 | |
| SCHEMBL6564885 | 0.87 | MRGPRX4 (0.34) | CYP4F2CYP4A11MAOBMRGPRX4SMN1; SMN2 | |
| SCHEMBL6155784 | 0.87 | MRGPRX4 (0.47) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL6155781 | 0.87 | MRGPRX4 (0.47) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL6563996 | 0.83 | VDR (0.44) | CYP4F2CYP4A11MAOB | |
| SCHEMBL6563980 | 0.83 | VDR (0.44) | CYP4F2CYP4A11MAOB | |
| SCHEMBL6563985 | 0.83 | VDR (0.44) | CYP4F2CYP4A11MAOB | |
| SCHEMBL6563956 | 0.82 | MAOB (0.35) | MAOBALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235824-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-05-19 | — | — | EP | disclosed |
| US-6706725-B1 | BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-03-16 | — | — | US | disclosed |
| EP-1235824-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038320-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |