Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158792 | 1.00 | GBA1 (0.31) | GBA1 | |
| SCHEMBL6936524 | 1.00 | GBA1 (0.31) | GBA1 | |
| SCHEMBL6155838 | 1.00 | GBA1 (0.31) | GBA1 | |
| SCHEMBL10258976 | 0.82 | IDE (0.34) | — | |
| SCHEMBL7884693 | 0.82 | — | — | |
| SCHEMBL16801785 | 0.82 | — | — | |
| SCHEMBL7884469 | 0.82 | IDE (0.34) | — | |
| SCHEMBL13609345 | 0.82 | IDE (0.34) | — | |
| SCHEMBL10306469 | 0.82 | IDE (0.34) | — | |
| SCHEMBL14221957 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894805-B1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | AVENTIS PHARMA SA (FR) | 2005-02-09 | — | — | EP | disclosed |
| US-6812331-B2 | BACTERICIDES | AVENTIS PHARMA S.A. (FR) | 2004-11-02 | — | — | US | disclosed |
| US-6583119-B2 | Aromatic antibiotics such as 7-((6-deoxy-5-methyl-4-methyl-hexopyranosyl)oxy)-4-hydroxy-8-methyl-3-(1 -(phenoxyimino) ethyl)-2H-1-benzopyran-2-one (2-propynyloxy)-carbamic 3'-ester acid, for prevention of grampositive bacterial infections | AVENTIS PHARMA S.A. (FR) | 2003-06-24 | — | — | US | disclosed |
| US-6579902-B1 | Antibiotic; ethoxy-carbamic acid 3'-ester of N-(7-((6-deoxy-5-C-methyl-4-O- methyl-alpha-L-lyxo-hexopyranosyl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-1 -benzopyran-3-yl)-benzeneacetamide | AVENTIS PHARMA S.A. (FR) | 2003-06-17 | — | — | US | disclosed |
| US-20030060609-A1 | Novel aromatic amides, preparation method and application as medicines | AVENTIS PHARMA S.A. | 2003-03-27 | — | — | US | disclosed |
| US-6420538-B1 | COMPOUND FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | AVENTIS PHARMA S.A. (FR) | 2002-07-16 | — | — | US | disclosed |
| US-6350733-B1 | 4-HYDROXYBENZOPYRAN-2-ONE DERIVATIVES; BACTERICIDES FOR STAPHYLOCOCCUS INFECTIONS; SKIN DISORDERS | AVENTIS PHARMA S.A. (FR) | 2002-02-26 | — | — | US | disclosed |
| US-20020010322-A1 | New aromatic derivatives substituted by a ribose, their preparation process and their use as medicaments | AVENTIS PHARMA S.A. | 2002-01-24 | — | — | US | disclosed |
| EP-0906326-B1 | NOVEL AROMATIC DERIVATIVES SUBSTITUTED BY A RIBOSE, THEIR METHOD OF PREPARATION AND APPLICATION AS MEDICINE | AVENTIS PHARMA SA (FR) | 2001-11-21 | — | — | EP | disclosed |
| US-5968939-A | ANTIBIOTICS FROM AMINOOXOBENZOPYRAN COMPOUNDS | HOECHST MARION ROUSSEL (FR) | 1999-10-19 | — | — | US | disclosed |
| EP-0906326-A1 | NOVEL AROMATIC DERIVATIVES SUBSTITUTED BY A RIBOSE, THEIR METHOD OF PREPARATION AND APPLICATION AS MEDICINE | HOECHST MARION ROUSSEL (FR) | 1999-04-07 | — | — | EP | disclosed |
| EP-0894805-A1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | HOECHST MARION ROUSSEL (FR) | 1999-02-03 | — | — | EP | disclosed |
| WO-1997047634-A1 | NOVEL AROMATIC DERIVATIVES SUBSTITUTED BY A RIBOSE, THEIR METHOD OF PREPARATION AND APPLICATION AS MEDICINE | HOECHST MARION ROUSSEL (FR) | 1997-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030060609-A1 | Novel aromatic amides, preparation method and application as medicines | NRDC, NPR1, NR4A1 | GBA1 2311/4885 |
| US-20020010322-A1 | New aromatic derivatives substituted by a ribose, their preparation process and their use as medicaments | RPIA, CD38, PARP1 | GBA1 578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.