Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HMGCR | P04035 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29514451 | 0.85 | HTT (0.62) | MEN1KMT2AHMGCRMAPTHTT | |
| SCHEMBL5743965 | 0.85 | HTT (0.62) | MEN1KMT2AHMGCRMAPTHTT | |
| SCHEMBL31098753 | 0.82 | THRA (0.48) | HMGCRMAPTKDM4EHSD17B10TSHR | |
| SCHEMBL7521761 | 0.80 | HSP90AB1 (0.60) | MEN1KMT2AHMGCRMAPTNPSR1 | |
| SCHEMBL9579295 | 0.77 | HMGCR (0.56) | MEN1KMT2AHMGCRMAPTHTT | |
| SCHEMBL6156200 | 0.77 | MAPT (0.42) | MAPTHTTNPSR1KDM4EHSD17B10 | |
| SCHEMBL6156205 | 0.77 | MAPT (0.42) | MAPTHTTNPSR1KDM4EHSD17B10 | |
| SCHEMBL27823240 | 0.76 | CYP2C19 (0.50) | KMT2AHMGCRMAPTNPSR1KDM4E | |
| SCHEMBL28553589 | 0.76 | MTNR1A (0.50) | MEN1KMT2AMAPTHTTNPSR1 | |
| SCHEMBL2091365 | 0.76 | MEN1 (0.60) | MEN1KMT2AHMGCRMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |