Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 11/20 | 0.49 |
| ▸ | MGAM | O43451 | 10/20 | 0.49 |
| ▸ | AMY1A | P0DUB6 | 10/20 | 0.49 |
| ▸ | SI | P14410 | 10/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 10/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19911626 | 0.85 | KMT2A (0.48) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL19911632 | 0.82 | KMT2A (0.46) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL7646751 | 0.81 | GAA (0.44) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL7232454 | 0.79 | HCAR3 (0.53) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL27380658 | 0.79 | KMO (0.57) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL7239851 | 0.77 | MGAM (0.41) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL170673 | 0.74 | GAA (0.71) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL17103034 | 0.74 | POLB (0.53) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL3840404 | 0.73 | GAA (0.69) | GAAMGAMAMY1ASIMGAM2 | |
| Hydrochloric Acid SCHEMBL10363645 | 0.73 | GAA (0.69) | GAAMGAMAMY1ASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569646-A2 | PIPERIDINE DERIVATIVES AS CCR5 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004054974-A2 | PIPERIDINE DERIVATIVES AS CCR5 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-07-01 | — | — | WO | disclosed |