Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.53 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155991 | 1.00 | VDR (0.53) | VDRP4HBTTRBACE1 | |
| SCHEMBL2783411 | 1.00 | VDR (0.53) | VDRP4HBTTRBACE1 | |
| SCHEMBL6155999 | 1.00 | VDR (0.53) | VDRP4HBTTRBACE1 | |
| SCHEMBL2783412 | 1.00 | VDR (0.53) | VDRP4HBTTRBACE1 | |
| SCHEMBL6155207 | 0.88 | VDR (0.40) | VDRP4HBTTR | |
| SCHEMBL6155213 | 0.88 | VDR (0.40) | VDRP4HBTTR | |
| SCHEMBL6155209 | 0.88 | VDR (0.40) | VDRP4HBTTR | |
| SCHEMBL6884038 | 0.88 | VDR (0.40) | VDRP4HBTTR | |
| SCHEMBL6155204 | 0.88 | VDR (0.40) | VDRP4HBTTR | |
| SCHEMBL6156305 | 0.82 | VDR (0.60) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | claimed |
| EP-1501843-A1 | ALKARYL-SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-02-02 | — | — | EP | claimed |
| WO-2003091265-A1 | ALKARYL-SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-11-06 | — | — | WO | claimed |
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| EP-1242471-A1 | SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001042315-A1 | SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2001-06-14 | — | — | WO | disclosed |