Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 3/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155209 | 1.00 | VDR (0.40) | VDRP4HBTTRKDM1APTGS1 | |
| SCHEMBL6155207 | 1.00 | VDR (0.40) | VDRP4HBTTRKDM1APTGS1 | |
| SCHEMBL6155213 | 1.00 | VDR (0.40) | VDRP4HBTTRKDM1APTGS1 | |
| SCHEMBL6155204 | 1.00 | VDR (0.40) | VDRP4HBTTRKDM1APTGS1 | |
| SCHEMBL6155994 | 0.88 | VDR (0.53) | VDRP4HBTTR | |
| SCHEMBL2783411 | 0.88 | VDR (0.53) | VDRP4HBTTR | |
| SCHEMBL6155991 | 0.88 | VDR (0.53) | VDRP4HBTTR | |
| SCHEMBL2783412 | 0.88 | VDR (0.53) | VDRP4HBTTR | |
| SCHEMBL6155999 | 0.88 | VDR (0.53) | VDRP4HBTTR | |
| SCHEMBL6156332 | 0.81 | VDR (0.59) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | claimed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | claimed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | claimed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |