Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 8/20 | 0.48 |
| ▸ | CA9 | Q16790 | 8/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5345045 | 0.73 | MAOB (0.77) | MAOBKDM4EALDH1A1GLAHPGD | |
| SCHEMBL6159090 | 0.73 | MAOB (0.67) | MAOBKDM4EALDH1A1GLAHPGD | |
| SCHEMBL4187220 | 0.72 | MAOB (1.00) | MAOBKDM4EALDH1A1GLAHPGD | |
| SCHEMBL6155496 | 0.70 | MAOB (0.73) | MAOBKDM4EALDH1A1GLAHPGD | |
| SCHEMBL31139188 | 0.70 | MAOB (0.73) | MAOBKDM4EALDH1A1GLAHPGD | |
| SCHEMBL3433162 | 0.69 | MAOB (0.74) | MAOBKDM4EALDH1A1GLAHPGD | |
| SCHEMBL876286 | 0.69 | MCL1 (0.73) | MAOBKDM4EALDH1A1GLAHPGD | |
| SCHEMBL15984890 | 0.68 | KDM4E (0.64) | MAOBKDM4EALDH1A1GLAHPGD | |
| SCHEMBL22840392 | 0.67 | MAOB (0.67) | MAOBKDM4EALDH1A1GLAHPGD | |
| SCHEMBL12938630 | 0.67 | TERT (0.47) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894805-B1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | AVENTIS PHARMA SA (FR) | 2005-02-09 | — | — | EP | disclosed |
| US-5968939-A | ANTIBIOTICS FROM AMINOOXOBENZOPYRAN COMPOUNDS | HOECHST MARION ROUSSEL (FR) | 1999-10-19 | — | — | US | disclosed |
| EP-0894805-A1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | HOECHST MARION ROUSSEL (FR) | 1999-02-03 | — | — | EP | disclosed |