Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.46 |
| ▸ | ITGAV | P06756 | 3/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 9/20 | 0.43 |
| ▸ | ACE | P12821 | 8/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 8/20 | 0.43 |
| ▸ | CPA1 | P15085 | 7/20 | 0.43 |
| ▸ | TPH1 | P17752 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158614 | 0.89 | ITGB1 (0.47) | ITGB3ITGAVITGB1ITGA4ITGB7 | |
| SCHEMBL6184063 | 0.86 | MME (0.49) | ITGB1ITGA4ITGB7MMEACE | |
| SCHEMBL2851699 | 0.84 | TPH1 (0.60) | TPH1FNTAFNTBPGGT1B | |
| SCHEMBL2847859 | 0.84 | TPH1 (0.60) | TPH1FNTAFNTBPGGT1B | |
| SCHEMBL2847857 | 0.84 | TPH1 (0.60) | TPH1FNTAFNTBPGGT1B | |
| SCHEMBL2847849 | 0.82 | PPARG (0.58) | ITGB1ITGA4ITGB7MMEACE | |
| SCHEMBL2849845 | 0.82 | PPARG (0.58) | ITGB1ITGA4ITGB7MMEACE | |
| SCHEMBL2853135 | 0.82 | ACE (0.56) | ITGB3ITGAVITGB1ITGA4ITGB7 | |
| SCHEMBL2853142 | 0.82 | ACE (0.56) | ITGB3ITGAVITGB1ITGA4ITGB7 | |
| SCHEMBL2849821 | 0.82 | PPARG (0.58) | ITGB1ITGA4ITGB7MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575911-A2 | BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004046091-A2 | BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-06-03 | — | — | WO | disclosed |