Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.49 |
| ▸ | MMEL1 | Q495T6 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | ACE | P12821 | 3/20 | 0.46 |
| ▸ | TPH1 | P17752 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.45 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.45 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.45 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.45 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.45 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.45 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.45 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184580 | 0.88 | PPARG (0.43) | MMEMMEL1FFAR1TPH1FNTA | |
| SCHEMBL6158614 | 0.88 | ITGB1 (0.47) | MMEFFAR1ACETPH1FNTA | |
| SCHEMBL2847859 | 0.86 | TPH1 (0.60) | TPH1FNTAFNTBPGGT1B | |
| SCHEMBL2847857 | 0.86 | TPH1 (0.60) | TPH1FNTAFNTBPGGT1B | |
| SCHEMBL2851699 | 0.86 | TPH1 (0.60) | TPH1FNTAFNTBPGGT1B | |
| SCHEMBL6156042 | 0.86 | ITGB3 (0.46) | MMEACETPH1FNTAFNTB | |
| SCHEMBL6158603 | 0.83 | TPH1 (0.49) | TPH1FNTAFNTBPGGT1B | |
| SCHEMBL2853812 | 0.83 | TPH1 (0.49) | TPH1FNTAFNTBPGGT1B | |
| SCHEMBL5383626 | 0.82 | PPARG (0.53) | — | |
| SCHEMBL5383617 | 0.82 | PPARG (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309575-B1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2005-06-08 | — | — | EP | claimed |
| EP-1309575-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | Galderma Research & Development (FR) | 2003-05-14 | — | — | EP | claimed |
| WO-2002012210-A9 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2002-04-18 | — | — | WO | claimed |
| WO-2002012210-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2002-02-14 | — | — | WO | claimed |
| EP-1309575-B1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2005-06-08 | — | — | EP | disclosed |
| EP-1309575-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | Galderma Research & Development (FR) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002012210-A9 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2002-04-18 | — | — | WO | disclosed |
| WO-2002012210-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2002-02-14 | — | — | WO | disclosed |