Bromide

Bromide

SCHEMBL615606

C1=CC([Zr+2]C2C=Cc3ccccc32)c2ccccc21.[Br-].[Br-]

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.35
CHRM1 known ✓ P11229 1/20 0.35
CHRM3 known ✓ P20309 1/20 0.35
ACHE known ✓ P22303 1/20 0.31
HTR2A P28223 2/20 0.43
HTR6 P50406 1/20 0.38
CYP2D6 P10635 3/20 0.37
KDM4E B2RXH2 4/20 0.35
HSD17B10 Q99714 3/20 0.35
TP53 P04637 2/20 0.35
CYP3A4 P08684 2/20 0.35
LMNA P02545 2/20 0.35
BRD4 O60885 1/20 0.35
CCL2 P13500 1/20 0.35
DRD2 P14416 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
NFKB1 P19838 1/20 0.35
SLC6A2 P23975 1/20 0.35
HTR2C P28335 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31357303 0.98 HTR2A (0.40) HTR2AHTR6CYP2D6KDM4EHSD17B10
Ethylene SCHEMBL818950 0.96 HTR2A (0.41) HTR2AHTR6CYP2D6KDM4EHSD17B10
Hydrochloric Acid SCHEMBL29424565 0.95 HTR2A (0.39) HTR2AHTR6CYP2D6KDM4EHSD17B10
Hydrochloric Acid SCHEMBL137960 0.95 HTR2A (0.39) HTR2AHTR6CYP2D6KDM4EHSD17B10
Fluoride Ion SCHEMBL1130379 0.95 HTR2A (0.39) HTR2AHTR6CYP2D6KDM4EHSD17B10
SCHEMBL3838138 0.95 HTR2A (0.39) HTR2AHTR6CYP2D6KDM4EHSD17B10
Ethylene SCHEMBL6918048 0.94 HTR2A (0.39) HTR2AHTR6CYP2D6KDM4EHSD17B10
Hydrochloric Acid SCHEMBL30533388 0.93 HTR2A (0.38) HTR2AHTR6CYP2D6KDM4EHSD17B10
Hydrochloric Acid SCHEMBL820052 0.93 HTR2A (0.38) HTR2AHTR6CYP2D6KDM4EHSD17B10
Ethylene SCHEMBL6914314 0.91 HTR2A (0.36) HTR2AHTR6CYP2D6KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6867212-B2 6-(1-fluoroethyl)-5-iodo-4-aminopyrimidine compounds process for preparation of the same and pest controllers for agricultural and horticultural use UBE INDUSTRIES, LTD. (JP) 2005-03-15 US claimed
EP-4688795-A1 A HIGHLY EFFICIENT PROCESS FOR THE RECOVERY AND CONVERSION OF METHYLALUMINOXANE RESIDUES LANXESS Organometallics GmbH (DE) 2026-02-11 EP disclosed
WO-2024200632-A1 A HIGHLY EFFICIENT PROCESS FOR THE RECOVERY AND CONVERSION OF METHYLALUMINOXANE RESIDUES LANXESS ORGANOMETALLICS GMBH (DE) 2024-10-03 WO disclosed
EP-4438609-A1 A HIGHLY EFFICIENT PROCESS FOR THE RECOVERY AND CONVERSION OF METHYLALUMINOXANE RESIDUES LANXESS Organometallics GmbH (DE) 2024-10-02 EP disclosed
EP-3480258-B1 SOLID MAO COMPOSITION CONTAINING AL2O3 AND METHOD FOR PRODUCING SAME TOSOH FINECHEM CORP (JP) 2023-12-20 EP disclosed
US-10870715-B2 Solid polyaluminoxane composition, olefin polymerization catalyst, olefin polymer production method and solid polyaluminoxane composition production method MITSUI CHEMICALS, INC. (JP) 2020-12-22 US disclosed
US-10793652-B2 Solid PMAO composition and method for producing same TOSOH FINECHEM CORPORATION (JP) 2020-10-06 US disclosed
US-10730969-B2 Solid MAO composition containing Al2O3 and method for producing same TOSOH FINECHEM CORPORATION (JP) 2020-08-04 US disclosed
US-10604604-B2 Multimodal polyolefin resin, and molded body manufactured therefrom DAELIM INDUSTRIAL CO., LTD. (KR) 2020-03-31 US disclosed
EP-3239196-B1 MULTIMODAL POLYOLEFIN RESIN HAVING HIGH MELT STRENGTH AND MOLDED PRODUCT PREPARED WITH THE SAME DAELIM IND CO LTD (KR) 2019-08-28 EP disclosed
EP-0327649-A1 CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR ITS PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-08-16 EP disclosed
EP-0328348-A2 Olefin polymerization catalyst and process for the polymerization of olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-08-16 EP disclosed
EP-0324856-A1 PROCESS FOR POLYMERIZING OLEFIN MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-07-26 EP disclosed
EP-0314797-A1 OLEFIN POLYMERIZATION CATALYST AND PROCESS FOR POLYMERIZING OLEFIN MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-05-10 EP disclosed
EP-0295312-A1 SOLID CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR ITS PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-12-21 EP disclosed
EP-0294942-A1 Solid catalyst for polymerizing an olefin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-12-14 EP disclosed
EP-0287666-A1 PROCESS FOR POLYMERIZING OLEFINS Mitsui Chemicals, Inc. (JP) 1988-10-26 EP disclosed
EP-0285443-A1 Process for producing solid catalyst for polymerization of olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-10-05 EP disclosed
EP-0279863-A1 CATALYST FOR POLYMERIZING ALPHA-OLEFIN AND POLYMERIZATION PROCESS MITSUI CHEMICALS, INC. (JP) 1988-08-31 EP disclosed
EP-0279586-A2 Finely divided aluminoxane, process for producing same and its use MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-08-24 EP disclosed