Ethylene

Ethylene

SCHEMBL818950

C1=CC([Zr+2]C2C=Cc3ccccc32)c2ccccc21.C=C.[Br-].[Br-]

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Ethylene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.33
CHRM1 known ✓ P11229 1/20 0.33
CHRM3 known ✓ P20309 1/20 0.33
HTR2A P28223 2/20 0.41
HTR6 P50406 1/20 0.36
CYP2D6 P10635 2/20 0.35
KDM4E B2RXH2 3/20 0.33
TP53 P04637 2/20 0.33
CYP3A4 P08684 2/20 0.33
HSD17B10 Q99714 2/20 0.33
BRD4 O60885 1/20 0.33
CCL2 P13500 1/20 0.33
LMNA P02545 1/20 0.33
DRD2 P14416 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
NFKB1 P19838 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL6918048 0.98 HTR2A (0.39) HTR2AHTR6CYP2D6KDM4ETP53
Ethylene SCHEMBL781726 0.96 HTR2A (0.36) HTR2AHTR6CYP2D6KDM4ETP53
Ethylene SCHEMBL6914314 0.96 HTR2A (0.36) HTR2AHTR6CYP2D6KDM4ETP53
Bromide SCHEMBL615606 0.96 HTR2A (0.43) HTR2AHTR6CYP2D6KDM4ETP53
Ethylene SCHEMBL6914267 0.94 HTR2A (0.35) HTR2AHTR6CYP2D6BRD4CCL2
SCHEMBL31357303 0.94 HTR2A (0.40) HTR2AHTR6CYP2D6KDM4ETP53
Ethylene SCHEMBL6910508 0.92 BRD4 (0.35) HTR2AHTR6CYP2D6KDM4ETP53
SCHEMBL3838138 0.91 HTR2A (0.39) HTR2AHTR6CYP2D6KDM4ETP53
Fluoride Ion SCHEMBL1130379 0.91 HTR2A (0.39) HTR2AHTR6CYP2D6KDM4ETP53
Hydrochloric Acid SCHEMBL29424565 0.91 HTR2A (0.39) HTR2AHTR6CYP2D6KDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3480258-B1 SOLID MAO COMPOSITION CONTAINING AL2O3 AND METHOD FOR PRODUCING SAME TOSOH FINECHEM CORP (JP) 2023-12-20 EP disclosed
US-10730969-B2 Solid MAO composition containing Al2O3 and method for producing same TOSOH FINECHEM CORPORATION (JP) 2020-08-04 US disclosed
EP-3480258-A1 SOLID MAO COMPOSITION CONTAINING AL2O3 AND METHOD FOR PRODUCING SAME Tosoh Finechem Corporation (JP) 2019-05-08 EP disclosed
US-20180355077-A1 SOLID MAO COMPOSITION CONTAINING AL2O3 AND METHOD FOR PRODUCING SAME TOSOH FINECHEM CORPORATION (JP) 2018-12-13 US disclosed
EP-2570437-B1 SOLID SUPPORT-POLYMETHYLALUMINOXANE COMPLEX, METHOD FOR PRODUCING SAME, OLEFIN POLYMERIZATION CATALYST, AND METHOD FOR PRODUCING POLYOLEFIN TOSOH FINECHEM CORP (JP) 2018-07-04 EP disclosed
EP-2360191-B1 SOLID POLYMETHYLALUMINOXANE COMPOSITION AND PROCESS FOR PRODUCING SAME TOSOH FINECHEM CORP (JP) 2017-03-29 EP disclosed
EP-2862889-B1 METHOD FOR PRODUCING SOLID POLYMETHYLALUMINOXANE COMPOSITION HAVING SMALL PARTICLE DIAMETER TOSOH FINECHEM CORP (JP) 2017-01-04 EP disclosed
US-9340630-B2 Method for manufacturing a small particle diameter product of solid polymethylaluminoxane composition TOSOH FINECHEM CORPORATION (JP) 2016-05-17 US disclosed
EP-2862889-A1 METHOD FOR PRODUCING SOLID POLYMETHYLALUMINOXANE COMPOSITION HAVING SMALL PARTICLE DIAMETER Tosoh Finechem Corporation (JP) 2015-04-22 EP disclosed
US-8975209-B2 Solid support-polymethylaluminoxane complex, method for producing same, olefin polymerization catalyst, and method for producing polyolefin TOSOH FINECHEM CORPORATION (JP) 2015-03-10 US disclosed
EP-1008626-A1 Hollow vessel for heat sterilization Mitsui Chemicals, Inc. (JP) 2000-06-14 EP disclosed
EP-0927201-A1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM Hyundai Petrochemical Co., Ltd. (KR) 1999-07-07 EP disclosed
EP-0530908-B1 Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM NV (NL) 1999-04-21 EP disclosed
US-5770655-A ACRYLATE MONOMER WITH MULTICYCLIC FUSED RING IN ESTER GROUP, OPTICAL FIBERS AND DISKS, CLARITY AND IMPACT STRENGTH, TETRACYCLODODECYL ACRYLATE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-06-23 US disclosed
EP-0671433-B1 Polymer composition and core-shell elastomer used therefor MITSUI CHEMICALS INC (JP) 1998-06-17 EP disclosed
WO-1998009996-A1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM HYUNDAI PETROCHEMICAL CO., LTD. (KR) 1998-03-12 WO disclosed
US-5646083-A Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM N.V. (NL) 1997-07-08 US disclosed
US-5574100-A ALPHA-OLEFIN-CYCLIC OLEFIN COPOLYMER, BUTADIENE-STYRENE COPOLYMER CORE, ALICYCLIC ACRYLATE SHELL MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-11-12 US disclosed
EP-0671433-A1 Polymer composition and core-shell elastomer used therefor MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-09-13 EP disclosed
EP-0530908-A1 Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM N.V. (NL) 1993-03-10 EP disclosed