Hydrochloric Acid

Hydrochloric Acid

SCHEMBL820052

C1=CC([Zr+2]C2C=Cc3ccccc32)c2ccccc21.[Cl-].[H-]

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.31
CHRM1 known ✓ P11229 1/20 0.31
CHRM3 known ✓ P20309 1/20 0.31
SLC6A2 known ✓ P23975 1/20 0.31
SLC6A3 known ✓ Q01959 1/20 0.31
HTR2A P28223 2/20 0.38
HTR6 P50406 1/20 0.37
BRD4 O60885 1/20 0.34
CCL2 P13500 1/20 0.34
CYP2D6 P10635 2/20 0.33
KDM4E B2RXH2 3/20 0.31
TP53 P04637 2/20 0.31
CYP3A4 P08684 2/20 0.31
HSD17B10 Q99714 2/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3838138 0.98 HTR2A (0.39) HTR2AHTR6BRD4CCL2CYP2D6
Hydrochloric Acid SCHEMBL137960 0.98 HTR2A (0.39) HTR2AHTR6BRD4CCL2CYP2D6
Hydrochloric Acid SCHEMBL29424565 0.98 HTR2A (0.39) HTR2AHTR6BRD4CCL2CYP2D6
Ethylene SCHEMBL6914267 0.96 HTR2A (0.35) HTR2AHTR6BRD4CCL2CYP2D6
Hydrochloric Acid SCHEMBL30533388 0.96 HTR2A (0.38) HTR2AHTR6BRD4CCL2CYP2D6
SCHEMBL31357303 0.96 HTR2A (0.40) HTR2AHTR6BRD4CCL2CYP2D6
Ethylene SCHEMBL781726 0.94 HTR2A (0.36) HTR2AHTR6BRD4CCL2CYP2D6
Ethylene SCHEMBL6914314 0.94 HTR2A (0.36) HTR2AHTR6BRD4CCL2CYP2D6
Hydrochloric Acid SCHEMBL5695982 0.94 BRD4 (0.37) HTR2AHTR6BRD4CCL2CYP2D6
Fluoride Ion SCHEMBL1130379 0.93 HTR2A (0.39) HTR2AHTR6BRD4CCL2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4688795-A1 A HIGHLY EFFICIENT PROCESS FOR THE RECOVERY AND CONVERSION OF METHYLALUMINOXANE RESIDUES LANXESS Organometallics GmbH (DE) 2026-02-11 EP disclosed
WO-2024200632-A1 A HIGHLY EFFICIENT PROCESS FOR THE RECOVERY AND CONVERSION OF METHYLALUMINOXANE RESIDUES LANXESS ORGANOMETALLICS GMBH (DE) 2024-10-03 WO disclosed
EP-4438609-A1 A HIGHLY EFFICIENT PROCESS FOR THE RECOVERY AND CONVERSION OF METHYLALUMINOXANE RESIDUES LANXESS Organometallics GmbH (DE) 2024-10-02 EP disclosed
EP-3480258-B1 SOLID MAO COMPOSITION CONTAINING AL2O3 AND METHOD FOR PRODUCING SAME TOSOH FINECHEM CORP (JP) 2023-12-20 EP disclosed
US-11485806-B2 Process for the preparation of polymerized polyethylene wax SCG CHEMICALS CO., LTD. (TH) 2022-11-01 US disclosed
US-10793652-B2 Solid PMAO composition and method for producing same TOSOH FINECHEM CORPORATION (JP) 2020-10-06 US disclosed
US-10730969-B2 Solid MAO composition containing Al2O3 and method for producing same TOSOH FINECHEM CORPORATION (JP) 2020-08-04 US disclosed
EP-3318544-B1 PROCESS FOR THE PREPARATION OF POLYMERIZED POLYETHYLENE WAX SCG CHEMICALS CO LTD (TH) 2020-03-18 EP disclosed
US-20190263947-A1 PROCESS FOR THE PREPARATION OF POLYMERIZED POLYETHYLENE WAX SCG CHEMICALS CO., LTD. (TH) 2019-08-29 US disclosed
US-20190153127-A1 SOLID PMAO COMPOSITION AND METHOD FOR PRODUCING SAME TOSOH FINECHEM CORPORATION (JP) 2019-05-23 US disclosed
EP-0327649-A1 CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR ITS PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-08-16 EP disclosed
EP-0328348-A2 Olefin polymerization catalyst and process for the polymerization of olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-08-16 EP disclosed
EP-0324856-A1 PROCESS FOR POLYMERIZING OLEFIN MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-07-26 EP disclosed
EP-0314797-A1 OLEFIN POLYMERIZATION CATALYST AND PROCESS FOR POLYMERIZING OLEFIN MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-05-10 EP disclosed
EP-0295312-A1 SOLID CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR ITS PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-12-21 EP disclosed
EP-0294942-A1 Solid catalyst for polymerizing an olefin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-12-14 EP disclosed
EP-0287666-A1 PROCESS FOR POLYMERIZING OLEFINS Mitsui Chemicals, Inc. (JP) 1988-10-26 EP disclosed
EP-0285443-A1 Process for producing solid catalyst for polymerization of olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-10-05 EP disclosed
EP-0279863-A1 CATALYST FOR POLYMERIZING ALPHA-OLEFIN AND POLYMERIZATION PROCESS MITSUI CHEMICALS, INC. (JP) 1988-08-31 EP disclosed
EP-0279586-A2 Finely divided aluminoxane, process for producing same and its use MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-08-24 EP disclosed