Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.60 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | NEK2 | P51955 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.40 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4629826 | 1.00 | PARP10 (0.60) | PARP10CHEK2SENP8SENP6HRH1 | |
| SCHEMBL4798997 | 0.90 | PARP10 (0.73) | PARP10CHEK2SENP8SENP6HRH1 | |
| Hydrochloric Acid SCHEMBL3636392 | 0.89 | PARP10 (0.71) | PARP10CHEK2SENP8SENP6HRH1 | |
| Trifluoroacetic Acid SCHEMBL23830909 | 0.86 | PARP10 (0.55) | PARP10SENP8SENP6MAP4K4FAAH | |
| Trifluoroacetic Acid SCHEMBL2823895 | 0.83 | HRH1 (0.53) | PARP10CHEK2HRH1EPHX2KCNH2 | |
| SCHEMBL3133910 | 0.81 | PARP10 (0.64) | PARP10CHEK2SENP8SENP6MAP4K4 | |
| Trifluoroacetic Acid SCHEMBL4233307 | 0.81 | EPHX2 (0.50) | HRH1EPHX2KCNH2 | |
| Hydrochloric Acid SCHEMBL3127575 | 0.80 | PARP10 (0.62) | PARP10CHEK2SENP8SENP6MAP4K4 | |
| SCHEMBL4241025 | 0.79 | HRH1 (0.62) | PARP10CHEK2SENP8SENP6HRH1 | |
| Trifluoroacetic Acid SCHEMBL6703422 | 0.79 | HTR2C (0.51) | PARP10OPRK1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3440052-B1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | UNIV OF OULU (FI) | 2023-10-25 | — | — | EP | disclosed |
| US-20210346322-A1 | Compounds for use in the treatment of cancer | UNIVERSITY OF OULU (FI) | 2021-11-11 | — | — | US | disclosed |
| US-20190105289-A1 | Compounds for use in the treatment of cancer | UNIVERSITY OF OULU (FI) | 2019-04-11 | — | — | US | disclosed |
| EP-3440052-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | University Of Oulu (FI) | 2019-02-13 | — | — | EP | disclosed |
| WO-2017174879-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITY OF OULU (FI) | 2017-10-12 | — | — | WO | disclosed |
| US-20050182040-A1 | Benzamide derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1500643-A1 | BENZAMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210346322-A1 | Compounds for use in the treatment of cancer | PARP10, MACROD1, MACROD2 | PARP10 1/4885CHEK2 2431/4885SENP8 4775/4885 |
| US-20190105289-A1 | Compounds for use in the treatment of cancer | PARP10, MACROD1, MACROD2 | PARP10 1/4885CHEK2 2431/4885SENP8 4775/4885 |
| US-20050182040-A1 | Benzamide derivatives | ROCK1, ROCK2, NHERF1 | PARP10 1211/4885CHEK2 2711/4885SENP8 3944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.