Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156479 | 0.94 | HSP90AB1 (0.53) | HSP90AB1 | |
| SCHEMBL8444451 | 0.85 | HSP90AB1 (0.45) | HSP90AB1 | |
| SCHEMBL6156198 | 0.85 | HSP90AB1 (0.57) | HSP90AB1POLBMAPTRECQLNPSR1 | |
| SCHEMBL8442613 | 0.85 | HSP90AB1 (0.57) | HSP90AB1POLBMAPTRECQLNPSR1 | |
| SCHEMBL6156108 | 0.84 | HSP90AB1 (0.49) | HSP90AB1 | |
| SCHEMBL8444987 | 0.84 | HSP90AB1 (0.49) | HSP90AB1 | |
| SCHEMBL8444453 | 0.81 | HSP90AB1 (0.41) | HSP90AB1 | |
| SCHEMBL6156202 | 0.79 | HSP90AB1 (0.51) | HSP90AB1 | |
| SCHEMBL26780378 | 0.79 | HSP90AB1 (0.78) | HSP90AB1 | |
| SCHEMBL26781255 | 0.76 | HSP90AB1 (0.51) | HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894805-B1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | AVENTIS PHARMA SA (FR) | 2005-02-09 | — | — | EP | claimed |