SCHEMBL6156479

SCHEMBL6156479

CO[C@@H]1[C@H](OC(=O)c2ccc(C)[nH]2)[C@@H](Oc2ccc3c(N(C)C)cc(=O)oc3c2C)[C@@H](Oc2ccc3c(N(C)C)cc(=O)oc3c2C)OC1(C)C

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSP90AB1 P08238 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6156477 0.94 HSP90AB1 (0.61) HSP90AB1
SCHEMBL8444453 0.86 HSP90AB1 (0.41) HSP90AB1
SCHEMBL6156202 0.85 HSP90AB1 (0.51) HSP90AB1
SCHEMBL8444451 0.82 HSP90AB1 (0.45) HSP90AB1
SCHEMBL8442613 0.80 HSP90AB1 (0.57) HSP90AB1
SCHEMBL6156198 0.80 HSP90AB1 (0.57) HSP90AB1
SCHEMBL6156108 0.80 HSP90AB1 (0.49) HSP90AB1
SCHEMBL8444987 0.80 HSP90AB1 (0.49) HSP90AB1
SCHEMBL26780378 0.73 HSP90AB1 (0.78) HSP90AB1
SCHEMBL8445425 0.71 HSP90AB1 (0.39) HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0894805-B1 Ribose substituted aromatic derivatives, their preparation and use as medicaments AVENTIS PHARMA SA (FR) 2005-02-09 EP claimed