Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16831106 | 0.86 | SLC6A4 (0.42) | SLC6A4SLC6A2IDO1GRIA1GRIA2 | |
| SCHEMBL28879893 | 0.82 | IDO1 (0.39) | SLC6A4SLC6A2IDO1ERN1TYR | |
| SCHEMBL28879920 | 0.82 | SLC6A4 (0.42) | SLC6A4SLC6A2IDO1ERN1APOBEC3G | |
| SCHEMBL4290170 | 0.80 | TYR (0.39) | SLC6A4SLC6A2IDO1ERN1TYR | |
| SCHEMBL2120782 | 0.80 | KLF10 (0.50) | SLC6A4SLC6A2IDO1ERN1KLF10 | |
| SCHEMBL31318281 | 0.78 | SLC6A4 (0.40) | SLC6A4SLC6A2 | |
| SCHEMBL9984918 | 0.78 | SLC6A4 (0.44) | SLC6A4SLC6A2KLF10 | |
| SCHEMBL1477460 | 0.78 | SLC6A4 (0.40) | SLC6A4SLC6A2 | |
| SCHEMBL2616934 | 0.78 | SLC6A4 (0.43) | SLC6A4SLC6A2IDO1 | |
| SCHEMBL30822631 | 0.78 | IDO1 (0.41) | SLC6A4SLC6A2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1282636-C | Vitamin D analogues | GALDERMA RES & DEV (FR) | 2006-11-01 | — | — | CN | disclosed |
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| CN-1332711-A | Vitamin D analogues | GALDERMA RES & DEV (FR) | 2002-01-23 | — | — | CN | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |