Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.39 |
| ▸ | CTSL | P07711 | 5/20 | 0.36 |
| ▸ | CTSB | P07858 | 5/20 | 0.36 |
| ▸ | CTSH | P09668 | 4/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14261875 | 1.00 | CTSK (0.39) | CTSKCTSLCTSBCTSHLTA4H | |
| SCHEMBL12631778 | 1.00 | CTSK (0.39) | CTSKCTSLCTSBCTSHLTA4H | |
| SCHEMBL20030485 | 0.98 | CTSK (0.37) | CTSKCTSLCTSBCTSHLTA4H | |
| SCHEMBL27991241 | 0.98 | CTSK (0.37) | CTSKCTSLCTSBCTSHLTA4H | |
| SCHEMBL114230 | 0.89 | CTSK (0.35) | CTSKCTSLCTSBCTSHLTA4H | |
| SCHEMBL18125093 | 0.87 | — | — | |
| SCHEMBL14928915 | 0.87 | — | — | |
| SCHEMBL4284276 | 0.87 | — | — | |
| SCHEMBL3155857 | 0.85 | CYP1A2 (0.40) | CTSKCTSLCTSBCTSHLTA4H | |
| SCHEMBL24199 | 0.82 | CTSK (0.36) | CTSKCTSLCTSBCTSHLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200546-B1 | ESTERS AND DIESTERS OF 3-CYCLOHEXYL-2-METHYL-1-PROPANOL, PERFUMED ARTICLES CONTAINING THEM AND METHOD OF IMPARTING FRAGRANCE | BUSH BOAKE ALLEN INC (US) | 2005-02-02 | — | — | EP | claimed |
| EP-1200546-A4 | FRAGRANCE MATERIALS | BUSH BOAKE ALLEN INC (US) | 2003-07-16 | — | — | EP | claimed |
| EP-1200546-A1 | FRAGRANCE MATERIALS | Bush Boake Allen Inc. (US) | 2002-05-02 | — | — | EP | claimed |
| US-6187727-B1 | USE OF 2-METHYL-3-CYCLOHEXYLPROPANOL, ESTERS THEREOF OR MIXTURES THEREOF | BUSH BOAKE ALLEN, INC. | 2001-02-13 | — | — | US | claimed |
| WO-2001004253-A1 | FRAGRANCE MATERIALS | BUSH BOAKE ALLEN INC. (US) | 2001-01-18 | — | — | WO | claimed |
| US-4197318-A | CYCLOHEXYL SUBSTITUTED ALKANOLS AS POTENTIATORS | JOHNSON & JOHNSON (US) | 1980-04-08 | — | — | US | claimed |
| US-4091090-A | PENETRANT ACCELERATOR COMPRISING CYCLOHEXYL-SUBSTITUTED ALKANOLS | JOHNSON & JOHNSON (US) | 1978-05-23 | — | — | US | claimed |
| US-4006218-A | MICROBIOCIDE | JOHNSON & JOHNSON (US) | 1977-02-01 | — | — | US | claimed |
| US-11655216-B2 | Aryl and heteroaryl ether derivatives as liver X receptor beta agonists, compositions, and their use | MERCK SHARP & DOHME LLC (US) | 2023-05-23 | — | — | US | disclosed |
| US-9650362-B2 | Inhibitors | PROBIODRUG AG (DE) | 2017-05-16 | — | — | US | disclosed |
| US-9505783-B2 | Method of producing pyrone and pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2016-11-29 | — | — | US | disclosed |
| US-20160002211-A1 | METHOD OF PRODUCING PYRONE AND PYRIDONE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2016-01-07 | — | — | US | disclosed |
| US-9173885-B2 | Inhibitors | PROBIODRUG AG (DE) | 2015-11-03 | — | — | US | disclosed |
| US-20150031876-A1 | METHOD FOR PRODUCING PYRONE AND PYRIDONE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2015-01-29 | — | — | US | disclosed |
| WO-2001004253-A1 | FRAGRANCE MATERIALS | BUSH BOAKE ALLEN INC. (US) | 2001-01-18 | — | — | WO | disclosed |
| US-4474748-A | ANTIBIOTICS, FUNGICIDES, ANTISEPTICS | JOHNSON & JOHNSON (US) | 1984-10-02 | — | — | US | disclosed |
| US-4321257-A | Potentiated medicaments | JOHNSON & JOHNSON (US) | 1982-03-23 | — | — | US | disclosed |
| US-4197318-A | CYCLOHEXYL SUBSTITUTED ALKANOLS AS POTENTIATORS | JOHNSON & JOHNSON (US) | 1980-04-08 | — | — | US | disclosed |
| US-4091090-A | PENETRANT ACCELERATOR COMPRISING CYCLOHEXYL-SUBSTITUTED ALKANOLS | JOHNSON & JOHNSON (US) | 1978-05-23 | — | — | US | disclosed |
| US-4006218-A | MICROBIOCIDE | JOHNSON & JOHNSON (US) | 1977-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150031876-A1 | METHOD FOR PRODUCING PYRONE AND PYRIDONE DERIVATIVES | PNPO, PDXK, CYP3A5 | CTSK 1584/4885CTSL 3177/4885CTSB 2108/4885 |
| US-11655216-B2 | Aryl and heteroaryl ether derivatives as liver X receptor beta agonists, compositions, and their use | NR1H2, NR1H3, NR1H4 | CTSK 3783/4885CTSL 3232/4885CTSB 2824/4885 |
| US-20160002211-A1 | METHOD OF PRODUCING PYRONE AND PYRIDONE DERIVATIVES | PNPO, PDXK, CYP3A5 | CTSK 1680/4885CTSL 3259/4885CTSB 2236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.