Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976942 | 0.81 | PRCP (0.38) | PRCPKDM1AATMHTR2CTDP1 | |
| SCHEMBL655217 | 0.81 | HTR3A (0.43) | PRCPKDM1A | |
| SCHEMBL4169709 | 0.80 | SLC18A3 (0.42) | GID4PRCPKDM1AKMT2AHTR2A | |
| Hydrochloric Acid SCHEMBL4470943 | 0.79 | HTR3A (0.42) | PRCPKDM1AHTR2CHTR2AHTR2B | |
| SCHEMBL11540135 | 0.77 | RECQL (0.38) | MAPTNPSR1ALDH1A1 | |
| SCHEMBL5616363 | 0.77 | HTR2C (0.50) | MAPTKDM1AMEN1KMT2AHTR2C | |
| SCHEMBL4840001 | 0.69 | AHR (0.40) | KDM1AMEN1KMT2AALDH1A1 | |
| SCHEMBL20561359 | 0.67 | SMN1; SMN2 (0.37) | GID4MAPTATMHTR2CACHE | |
| SCHEMBL22416555 | 0.67 | HTR2A (0.35) | GID4MAPTPRCPKDM1AMEN1 | |
| SCHEMBL20561358 | 0.67 | SMN1; SMN2 (0.37) | GID4MAPTATMHTR2CACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937715-B1 | TETRAHYDROBENZINDOLE COMPOUNDS | MEIJI SEIKA KAISHA (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-6355642-B1 | PSYCHOLOGICAL DISORDERS AND BRAIN DISORDERS | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-03-12 | — | — | US | disclosed |
| EP-0937715-A1 | TETRAHYDROBENZINDOLE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1999-08-25 | — | — | EP | disclosed |