Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4473284 | 0.98 | SLC18A3 (0.41) | SLC18A3SIGMAR1PRCPGAARECQL | |
| SCHEMBL8976942 | 0.80 | PRCP (0.38) | PRCPRECQLKDM1ASLC6A2HTR2A | |
| SCHEMBL655217 | 0.80 | HTR3A (0.43) | PRCPKDM1ASLC6A2SLC6A4 | |
| SCHEMBL11540135 | 0.80 | RECQL (0.38) | RECQL | |
| SCHEMBL6156729 | 0.80 | GID4 (0.40) | PRCPKDM1AKMT2ASMN1; SMN2GID4 | |
| Hydrochloric Acid SCHEMBL4476677 | 0.79 | KDM1A (0.37) | PRCPRECQLKDM1ASLC6A2HTR2A | |
| Hydrochloric Acid SCHEMBL4470943 | 0.79 | HTR3A (0.42) | PRCPKDM1ASLC6A2HTR2ASLC6A4 | |
| SCHEMBL7070256 | 0.78 | SLC18A3 (0.45) | SLC18A3SIGMAR1PRCPKDM1ACISD1 | |
| SCHEMBL4528355 | 0.78 | SLC18A3 (0.45) | SLC18A3SIGMAR1PRCPKDM1ACISD1 | |
| SCHEMBL5616363 | 0.76 | HTR2C (0.50) | GAAKDM1AKMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4545066-A3 | 4-PHENYL-TETRAHYDROPYRIDINE DERIVATIVES FOR TREATING HEARING DISEASES | Cilcare Dev (FR) | 2025-06-25 | — | — | EP | disclosed |
| EP-4545066-A3 | 4-PHENYL-TETRAHYDROPYRIDINE DERIVATIVES FOR TREATING HEARING DISEASES | Cilcare Dev (FR) | 2025-06-25 | — | — | EP | disclosed |
| EP-4545066-A2 | 4-PHENYL-TETRAHYDROPYRIDINE DERIVATIVES FOR TREATING HEARING DISEASES | Cilcare Dev (FR) | 2025-04-30 | — | — | EP | disclosed |
| EP-4545066-A2 | 4-PHENYL-TETRAHYDROPYRIDINE DERIVATIVES FOR TREATING HEARING DISEASES | Cilcare Dev (FR) | 2025-04-30 | — | — | EP | disclosed |
| EP-4545066-A2 | 4-PHENYL-TETRAHYDROPYRIDINE DERIVATIVES FOR TREATING HEARING DISEASES | Cilcare Dev (FR) | 2025-04-30 | — | — | EP | disclosed |
| EP-4452267-B1 | 4-PHENYL-TETRAHYDROPYRIDINE DERIVATIVES FOR TREATING HEARING DISEASES | CILCARE DEV (FR) | 2025-04-23 | — | — | EP | disclosed |
| CN-118715014-A | 4-Phenyl-tetrahydropyridine derivatives for the treatment of hearing disorders | 西尔卡雷德夫公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-118715014-A | 4-Phenyl-tetrahydropyridine derivatives for the treatment of hearing disorders | 西尔卡雷德夫公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-118715014-A | 4-Phenyl-tetrahydropyridine derivatives for the treatment of hearing disorders | 西尔卡雷德夫公司 | 2024-09-27 | — | — | CN | disclosed |
| US-20230390273-A1 | 4-PHENYL-TETRAHYDROPYRIDINE DERIVATIVES FOR TREATING HEARING DISEASES | CILCARE DEV (FR) | 2023-12-07 | — | — | US | disclosed |
| EP-0107930-B1 | FUSED AROMATIC OXAZEPINONES AND SULPHUR ANALOGUES THEREOF AND THEIR PREPARATION AND USE IN COUNTERACTING HISTAMINE | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1990-11-28 | — | — | EP | disclosed |
| US-4812565-A | ANTIHISTAMINE INTERMEDIATES | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-14 | — | — | US | disclosed |
| US-4810795-A | ANTIHISTAMINES | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-07 | — | — | US | disclosed |
| US-4727152-A | Intermediates useful in the preparation of fused aromatic oxazepinones, thiazepinones, diazepinones and sulfur analogs thereof | A. H. ROBINS COMPANY, INC. (US) | 1988-02-23 | — | — | US | disclosed |
| US-4705853-A | ANTIHISTAMINES | A. H. ROBINS COMPANY, INC. (US) | 1987-11-10 | — | — | US | disclosed |
| US-4642343-A | ANTIHISTAMINES | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-02-10 | — | — | US | disclosed |
| US-4604388-A | Fused aromatic oxazepinones, thiazepinones, diazepinones and sulfur analogs thereof in a method of counteracting histamine | A. H. ROBINS COMPANY, INCORPORATED (US) | 1986-08-05 | — | — | US | disclosed |
| US-4592866-A | Fused aromatic oxazepinones, thiazepinones, diazepinones and sulfur analogs thereof | A. H. ROBINS COMPANY, INC. (US) | 1986-06-03 | — | — | US | disclosed |
| EP-0107930-A2 | Fused aromatic oxazepinones and sulphur analogues thereof and their preparation and use in counteracting histamine | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1984-05-09 | — | — | EP | disclosed |
| US-4278797-A | Intermediates to phenylmorphans and method of preparation thereof | ELI LILLY AND COMPANY (US) | 1981-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230390273-A1 | 4-PHENYL-TETRAHYDROPYRIDINE DERIVATIVES FOR TREATING HEARING DISEASES | OTC, PSEN1, SYPL1 | SLC18A3 140/4885SIGMAR1 3145/4885PRCP 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.