SCHEMBL6156794

CC(C)(CCCCCc1cccc(C=Cc2ccc(O[Si](C)(C)C(C)(C)C)c(O[Si](C)(C)C(C)(C)C)c2)c1)OC1OCCCC1=O

nearest known ligand 0.33

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	HMGCR	P04035	1/20	0.33

▸	ALOX5	P09917	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6157458	0.86	HMGCR (0.34)	HMGCR
SCHEMBL6879551	0.86	HMGCR (0.36)	HMGCR
SCHEMBL6157185	0.86	HMGCR (0.33)	HMGCR
SCHEMBL6156767	0.79	MGLL (0.35)	—
SCHEMBL6157460	0.78	BACE1 (0.33)	—
SCHEMBL6158268	0.78	BACE1 (0.33)	—
SCHEMBL6155888	0.76	HSP90AA1 (0.38)	HMGCR
SCHEMBL6160284	0.75	HMGCR (0.32)	HMGCR
SCHEMBL6155756	0.73	HMGCR (0.36)	HMGCR
SCHEMBL6881436	0.72	HMGCR (0.37)	HMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1124779-B1	VITAMIN D ANALOGUES	GALDERMA RES & DEV (FR)	2005-02-02	—	—	EP	disclosed
EP-1124779-A1	VITAMIN D ANALOGUES	Galderma Research & Development, S.N.C. (FR)	2001-08-22	—	—	EP	disclosed
WO-2000026167-A1	VITAMIN D ANALOGUES	GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR)	2000-05-11	—	—	WO	disclosed