Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157185 | 0.91 | HMGCR (0.33) | HMGCR | |
| SCHEMBL6156794 | 0.86 | HMGCR (0.33) | HMGCR | |
| SCHEMBL6881436 | 0.86 | HMGCR (0.37) | HMGCR | |
| SCHEMBL6158268 | 0.84 | BACE1 (0.33) | — | |
| SCHEMBL6157460 | 0.84 | BACE1 (0.33) | — | |
| SCHEMBL6155756 | 0.80 | HMGCR (0.36) | HMGCR | |
| SCHEMBL6156767 | 0.79 | MGLL (0.35) | — | |
| SCHEMBL6160284 | 0.77 | HMGCR (0.32) | HMGCR | |
| SCHEMBL6884487 | 0.77 | HMGCR (0.35) | HMGCR | |
| SCHEMBL6156155 | 0.76 | HMGCR (0.49) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |