Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 4/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157995 | 0.76 | CRBN (0.36) | DDB1CRBNALDH1A1 | |
| SCHEMBL829491 | 0.69 | ALDH1A1 (0.39) | ALDH1A1HPGDGAAMAPTALOX15 | |
| SCHEMBL4186361 | 0.68 | MAPT (0.43) | DDB1CRBNALDH1A1GAAMAPT | |
| SCHEMBL830519 | 0.65 | ALDH1A1 (0.38) | ALDH1A1HPGDGAAMAPTALOX15 | |
| SCHEMBL10911104 | 0.59 | PDE7A (0.33) | ALDH1A1 | |
| SCHEMBL830557 | 0.59 | ALDH1A1 (0.41) | ALDH1A1HPGDGAAMAPTALOX15 | |
| SCHEMBL3729724 | 0.58 | SRC (0.50) | ALDH1A1HPGDMAPTKDM4EDRD2 | |
| SCHEMBL7208190 | 0.58 | ALDH1A1 (0.47) | ALDH1A1HPGDGAAMAPTALOX15 | |
| SCHEMBL4906016 | 0.58 | ALDH1A1 (0.47) | ALDH1A1HPGDGAAMAPTALOX15 | |
| SCHEMBL12363022 | 0.57 | ALDH1A1 (0.78) | ALDH1A1HPGDGAAMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937715-B1 | TETRAHYDROBENZINDOLE COMPOUNDS | MEIJI SEIKA KAISHA (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-6355642-B1 | PSYCHOLOGICAL DISORDERS AND BRAIN DISORDERS | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-03-12 | — | — | US | disclosed |
| EP-0937715-A1 | TETRAHYDROBENZINDOLE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1999-08-25 | — | — | EP | disclosed |