SCHEMBL4906016

SCHEMBL4906016

CC(=O)c1ccc2c(c1O)CCCC2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
HPGD P15428 2/20 0.47
MAPT P10636 2/20 0.47
MAPK1 P28482 2/20 0.47
GAA P10253 1/20 0.47
ALOX15 P16050 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
KDM4E B2RXH2 2/20 0.42
BCL2L1 Q07817 1/20 0.41
BAD Q92934 1/20 0.41
NQO1 P15559 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
CTRC Q99895 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7208190 0.96 ALDH1A1 (0.47) ALDH1A1HPGDMAPTMAPK1GAA
SCHEMBL2787728 0.85 SELL (0.47) ALDH1A1HPGDMAPK1KDM4EBCL2L1
SCHEMBL368712 0.81 BCL2L1 (0.41) ALDH1A1HPGDMAPTMAPK1ALOX15
SCHEMBL23713391 0.81 SELL (0.47) ALDH1A1HPGDMAPTMAPK1TDP1
SCHEMBL6416867 0.81 PDK2 (0.42) ALDH1A1HPGDMAPTGAASMN1; SMN2
SCHEMBL19330760 0.77 PDK2 (0.42) ALDH1A1HPGDMAPTGAAALOX15
SCHEMBL27350945 0.77 HSP90AB1 (0.42) ALDH1A1HPGDMAPTMAPK1GAA
SCHEMBL20421306 0.77 ALDH1A1 (0.40) ALDH1A1HPGDMAPTMAPK1GAA
SCHEMBL9668378 0.76 BCL2L1 (0.37) MAPK1L3MBTL1BCL2L1BADNQO1
SCHEMBL31359858 0.76 BCL2L1 (0.52) ALDH1A1HPGDL3MBTL1KDM4EBCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3880683-B1 MONOHYDRATE POTASSIUM SALT OF A THIENOPYRIDONE DERIVATIVE AND ITS PREPARATION PROCESS POXEL (FR) 2023-11-01 EP claimed
CN-113166168-A Potassium salt monohydrate of thienopyridone derivative and preparation method thereof 博希尔公司 2021-07-23 CN claimed
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction BIODERM RESEARCH (US) 2008-10-16 US claimed
US-20060074108-A1 Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition BIODERM RESEARCH (US) 2006-04-06 US claimed
US-12319700-B2 Monohydrate potassium salt of a thienopyridone derivative and its preparation process POXEL (FR) 2025-06-03 US disclosed
US-12310949-B2 Use of a thienopyridone derivative in the treatment of autosomal dominant polycystic kidney disease (ADPKD) POXEL (FR) 2025-05-27 US disclosed
US-20250154164-A1 MONOHYDRATE POTASSIUM SALT OF A THIENOPYRIDONE DERIVATIVE AND ITS PREPARATION PROCESS POXEL (FR) 2025-05-15 US disclosed
CN-115335048-B Use of thienopyridone derivatives for the treatment of adrenoleukodystrophy or adrenomyeloneuropathy 博希尔公司 2025-04-04 CN disclosed
CN-115361949-B Use of thienopyridone derivatives in the treatment of autosomal dominant polycystic kidney disease ADPKD 博希尔公司 2025-03-11 CN disclosed
EP-4125885-B1 USE OF A THIENOPYRIDONE DERIVATIVE IN THE TREATMENT OF DIABETIC NEPHROPATHY POXEL (FR) 2024-12-25 EP disclosed
US-12162863-B2 Modulators of stimulator of interferon genes (STING) Ryvu Therapeutics S.A. (PL) 2024-12-10 US disclosed
EP-4125886-B1 USE OF THIENOPYRIDONE DERIVATIVES FOR THE TREATMENT OF ADRENOLEUCODYSTROPHY OR ADRENOMYELONEUROPATHY POXEL (FR) 2024-11-27 EP disclosed
CN-113166168-A Potassium salt monohydrate of thienopyridone derivative and preparation method thereof 博希尔公司 2021-07-23 CN disclosed
EP-3807264-A1 MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2021-04-21 EP disclosed
WO-2019238786-A1 MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2019-12-19 WO disclosed
US-8227426-B2 Chiral complexes of ascorbic acid with natural antioxidant and anti-inflammatory ketones including aloe, citrus, ginger, and mango for skin and hair care ISLAND KINETICS INC. (US) 2012-07-24 US disclosed
US-20110059907-A1 Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care ISLAND KINETICS INC. (US) 2011-03-10 US disclosed
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles BIODERM RESEARCH (US) 2008-10-16 US disclosed
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction BIODERM RESEARCH (US) 2008-10-16 US disclosed
US-20060074108-A1 Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition BIODERM RESEARCH (US) 2006-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110059907-A1 Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care GLA, LPO, PLOD3 ALDH1A1 110/4885HPGD 774/4885MAPT 2800/4885
US-12162863-B2 Modulators of stimulator of interferon genes (STING) STING1, IRF3, CGAS ALDH1A1 4462/4885HPGD 296/4885MAPT 1787/4885
US-12319700-B2 Monohydrate potassium salt of a thienopyridone derivative and its preparation process SLC10A1, SLC5A2, TALDO1 ALDH1A1 867/4885HPGD 171/4885MAPT 1184/4885
US-20250154164-A1 MONOHYDRATE POTASSIUM SALT OF A THIENOPYRIDONE DERIVATIVE AND ITS PREPARATION PROCESS SLC10A1, TALDO1, SLC5A2 ALDH1A1 918/4885HPGD 185/4885MAPT 1134/4885
US-12310949-B2 Use of a thienopyridone derivative in the treatment of autosomal dominant polycystic kidney disease (ADPKD) PKD1, PKD2, PFKP ALDH1A1 1520/4885HPGD 194/4885MAPT 1076/4885
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction PSMB1, PLOD3, CUTA ALDH1A1 330/4885HPGD 1094/4885MAPT 1630/4885
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles PROC, COL1A1, CUTA ALDH1A1 35/4885HPGD 725/4885MAPT 1443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.