Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | P4HB | P07237 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155892 | 0.87 | MAOB (0.58) | ERAP1KDM4EP4HBALDH1A1GLA | |
| SCHEMBL6156448 | 0.84 | PRKDC (0.64) | KDM4EP4HBALDH1A1GLAHPGD | |
| SCHEMBL6155495 | 0.81 | MAOB (0.51) | KDM4EP4HBALDH1A1GLAHPGD | |
| SCHEMBL5345045 | 0.72 | MAOB (0.77) | KDM4EALDH1A1GLAHPGDGAA | |
| SCHEMBL6158814 | 0.72 | PRKDC (0.37) | ERAP1KDM4EALDH1A1PDE3BPDE3A | |
| SCHEMBL28365890 | 0.71 | KMT2A (0.62) | KDM4EALDH1A1GAAKMT2AATM | |
| SCHEMBL4187220 | 0.71 | MAOB (1.00) | KDM4EALDH1A1GLAHPGDGAA | |
| SCHEMBL15836706 | 0.71 | KMT2A (0.69) | KDM4EP4HBALDH1A1GLAHPGD | |
| SCHEMBL15984890 | 0.70 | KDM4E (0.64) | ERAP1KDM4EP4HBALDH1A1GLA | |
| SCHEMBL6155496 | 0.70 | MAOB (0.73) | KDM4EALDH1A1GLAHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894805-B1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | AVENTIS PHARMA SA (FR) | 2005-02-09 | — | — | EP | disclosed |
| US-5968939-A | ANTIBIOTICS FROM AMINOOXOBENZOPYRAN COMPOUNDS | HOECHST MARION ROUSSEL (FR) | 1999-10-19 | — | — | US | disclosed |
| EP-0894805-A1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | HOECHST MARION ROUSSEL (FR) | 1999-02-03 | — | — | EP | disclosed |