Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | P4HB | P07237 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 7/20 | 0.51 |
| ▸ | CA9 | Q16790 | 7/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.51 |
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CCR4 | P51679 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156448 | 0.88 | PRKDC (0.64) | MAOBKDM4EALDH1A1GLAHPGD | |
| SCHEMBL6156974 | 0.87 | ERAP1 (0.58) | MAOBKDM4EALDH1A1GLAHPGD | |
| SCHEMBL6155495 | 0.85 | MAOB (0.51) | MAOBKDM4EALDH1A1GLAHPGD | |
| SCHEMBL16260714 | 0.78 | MAOB (0.48) | MAOBKDM4EALDH1A1GLAHPGD | |
| Hydrochloric Acid SCHEMBL16242701 | 0.77 | MAOB (0.47) | MAOBKDM4EALDH1A1GLAHPGD | |
| SCHEMBL5345045 | 0.76 | MAOB (0.77) | MAOBKDM4EALDH1A1GLAHPGD | |
| SCHEMBL6156411 | 0.76 | PRKDC (0.49) | PRKDC | |
| SCHEMBL6157322 | 0.75 | ERAP1 (0.52) | MAOBKDM4EALDH1A1GLAHPGD | |
| SCHEMBL28365890 | 0.75 | KMT2A (0.62) | KDM4EALDH1A1GAAPRKDCATM | |
| SCHEMBL4187220 | 0.75 | MAOB (1.00) | MAOBKDM4EALDH1A1GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894805-B1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | AVENTIS PHARMA SA (FR) | 2005-02-09 | — | — | EP | disclosed |
| US-5968939-A | ANTIBIOTICS FROM AMINOOXOBENZOPYRAN COMPOUNDS | HOECHST MARION ROUSSEL (FR) | 1999-10-19 | — | — | US | disclosed |
| EP-0894805-A1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | HOECHST MARION ROUSSEL (FR) | 1999-02-03 | — | — | EP | disclosed |