Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 6/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1829065 | 0.82 | LPL (0.47) | LPLLIPGTDP1MEN1TP53 | |
| SCHEMBL16487744 | 0.82 | LPL (0.47) | LPLLIPGTDP1MEN1TP53 | |
| SCHEMBL12338988 | 0.81 | LPL (0.46) | LPLLIPGTDP1MEN1TP53 | |
| SCHEMBL19809500 | 0.79 | LPL (0.47) | LPLLIPGTDP1MEN1TP53 | |
| SCHEMBL15978009 | 0.79 | LPL (0.41) | LPLLIPG | |
| SCHEMBL9885169 | 0.76 | LPL (0.39) | LPLLIPG | |
| SCHEMBL12447706 | 0.75 | ALOX5 (0.39) | LIPGTDP1MEN1TP53CYP3A4 | |
| SCHEMBL12715489 | 0.74 | LPL (0.45) | LPLLIPGGPR35 | |
| SCHEMBL12887133 | 0.74 | LPL (0.40) | LPLLIPG | |
| SCHEMBL16919575 | 0.74 | LPL (0.47) | LPLLIPGGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050165185-A1 | Preparation of a conjugated molecule and materials for use therein | MERCK PATENT GMBH (DE) | 2005-07-28 | — | — | US | disclosed |
| EP-1499662-A1 | PREPATION OF A CONJUGATED MOLECULE AND MATERIALS FOR USE THEREIN | Avecia Limited (GB) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003089499-A1 | PREPATION OF A CONJUGATED MOLECULE AND MATERIALS FOR USE THEREIN | AVECIA LIMITED (GB) | 2003-10-30 | — | — | WO | disclosed |