Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.52 |
| ▸ | CCR4 | P51679 | 4/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.48 |
| ▸ | ESR1 | P03372 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211529 | 0.76 | KDM4E (0.66) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL16260714 | 0.75 | MAOB (0.48) | ERAP1CCR4ESR2ESR1KDM4E | |
| SCHEMBL6155892 | 0.75 | MAOB (0.58) | ERAP1CCR4KDM4EALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL16242701 | 0.74 | MAOB (0.47) | ERAP1CCR4ESR2ESR1KDM4E | |
| SCHEMBL3766383 | 0.70 | KDM4E (0.74) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL27806711 | 0.67 | CCR4 (1.00) | CCR4 | |
| SCHEMBL28065504 | 0.66 | ESR2 (0.56) | ERAP1ESR2ESR1KDM4EALDH1A1 | |
| SCHEMBL6828759 | 0.66 | ESR2 (1.00) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL6825266 | 0.65 | ESR2 (1.00) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL7824164 | 0.65 | KDM4E (0.66) | ESR2ESR1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894805-B1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | AVENTIS PHARMA SA (FR) | 2005-02-09 | — | — | EP | disclosed |
| US-5968939-A | ANTIBIOTICS FROM AMINOOXOBENZOPYRAN COMPOUNDS | HOECHST MARION ROUSSEL (FR) | 1999-10-19 | — | — | US | disclosed |
| EP-0894805-A1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | HOECHST MARION ROUSSEL (FR) | 1999-02-03 | — | — | EP | disclosed |