Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574108 | 0.94 | CYP3A4 (0.56) | CYP3A4HSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL7699367 | 0.93 | CYP3A4 (0.58) | CYP3A4HSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL9514948 | 0.88 | MAPT (0.47) | CYP3A4HSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL3572819 | 0.88 | KMT2A (0.49) | CYP3A4HSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL11732644 | 0.86 | CYP3A4 (0.56) | CYP3A4HSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL8248139 | 0.86 | CYP3A4 (0.59) | CYP3A4HSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL9263319 | 0.86 | CYP3A4 (0.59) | CYP3A4HSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL9585882 | 0.85 | CYP3A4 (0.48) | CYP3A4HSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL3174279 | 0.85 | CYP3A4 (0.57) | CYP3A4HSD17B10MEN1USP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8497507 | 0.85 | CYP3A4 (0.58) | CYP3A4HSD17B10MEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916654-B1 | SULFONIC ESTER DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND USE THEREOF | KANEKA CORP (JP) | 2005-02-23 | — | — | EP | disclosed |
| US-6410773-B1 | OPTICAL ACTIVE MATERIAL; ENKEPHALINASE INHIBITORS; HYPOTENSIVE AGENTS | KANEKA CORPORATION (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6121477-A | Sulfonic ester derivatives, process for preparing the same, and use thereof | KANEKA CORPORATION (JP) | 2000-09-19 | — | — | US | disclosed |
| US-5945548-A | Process for the synthesis of α-substituted acrylic acids and their application | SOCIETE CIVILE BIOPROJECT (FR) | 1999-08-31 | — | — | US | disclosed |
| EP-0916654-A1 | SULFONIC ESTER DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND USE THEREOF | KANEKA CORPORATION (JP) | 1999-05-19 | — | — | EP | disclosed |
| US-5786494-A | Process for the synthesis of α-substituted acrylic acids and their application | SOCIETE CIVILE BIOPROJET (FR) | 1998-07-28 | — | — | US | disclosed |