Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9585882 | 0.90 | CYP3A4 (0.48) | MAPTMEN1USP2LMNAKMT2A | |
| SCHEMBL6157430 | 0.88 | CYP3A4 (0.58) | MAPTMEN1USP2LMNAKMT2A | |
| SCHEMBL9381254 | 0.87 | MAPT (0.46) | MAPTMEN1USP2LMNAKMT2A | |
| SCHEMBL9514872 | 0.83 | KDM4E (0.50) | MAPTUSP2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7574108 | 0.83 | CYP3A4 (0.56) | MAPTMEN1USP2LMNAKMT2A | |
| SCHEMBL7699367 | 0.82 | CYP3A4 (0.58) | MAPTMEN1USP2LMNAKMT2A | |
| SCHEMBL11006092 | 0.81 | MAPT (0.46) | MAPTMEN1USP2LMNAKMT2A | |
| SCHEMBL3572819 | 0.77 | KMT2A (0.49) | MAPTMEN1USP2LMNAKMT2A | |
| SCHEMBL14003499 | 0.76 | CYP3A4 (0.75) | MAPTUSP2LMNAKMT2AALDH1A1 | |
| SCHEMBL4140012 | 0.76 | RAB9A (0.58) | MAPTMEN1USP2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341409-B1 | Platinum (II) complexes, their preparation and use as antitumour agents | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-12-29 | — | — | EP | disclosed |