Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574108 | 0.88 | CYP3A4 (0.56) | KMT2AMEN1USP2ALDH1A1LMNA | |
| SCHEMBL6157430 | 0.88 | CYP3A4 (0.58) | KMT2AMEN1USP2ALDH1A1LMNA | |
| SCHEMBL7699367 | 0.84 | CYP3A4 (0.58) | KMT2AMEN1USP2ALDH1A1LMNA | |
| SCHEMBL6250712 | 0.79 | MDM2 (0.69) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL8248139 | 0.78 | CYP3A4 (0.59) | KMT2AMEN1USP2ALDH1A1LMNA | |
| SCHEMBL11732644 | 0.78 | CYP3A4 (0.56) | KMT2AMEN1USP2ALDH1A1LMNA | |
| SCHEMBL9263319 | 0.78 | CYP3A4 (0.59) | KMT2AMEN1USP2ALDH1A1LMNA | |
| SCHEMBL9381254 | 0.77 | MAPT (0.46) | KMT2AMEN1USP2ALDH1A1LMNA | |
| SCHEMBL12439954 | 0.77 | CYP3A4 (0.52) | KMT2AMEN1USP2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL8497507 | 0.77 | CYP3A4 (0.58) | KMT2AMEN1USP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741323-B2 | Indene derivatives and process for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-22 | — | — | US | disclosed |
| US-20070185109-A1 | Idene derivatives and process for the preparation thereof | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2007-08-09 | — | — | US | disclosed |
| EP-1740531-A1 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005100303-A1 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185109-A1 | Idene derivatives and process for the preparation thereof | INSR, PPARD, GPR119 | KMT2A 3388/4885MEN1 2055/4885USP2 4401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.