Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 1/20 | 0.50 |
| ▸ | PGK1 | P00558 | 1/20 | 0.44 |
| ▸ | PGK2 | P07205 | 1/20 | 0.44 |
| ▸ | PGD | P52209 | 3/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.39 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.39 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL11331805 | 1.00 | MPI (0.50) | MPIPGK1PGK2PGDLPAR1 | |
| Phosphoric Acid SCHEMBL7132362 | 1.00 | MPI (0.50) | MPIPGK1PGK2PGDLPAR1 | |
| Phosphoric Acid SCHEMBL6754811 | 0.89 | MPI (0.61) | MPIPGK1PGK2PGDLPAR1 | |
| Phosphoric Acid SCHEMBL17103808 | 0.89 | MPI (0.61) | MPIPGK1PGK2PGDLPAR1 | |
| SCHEMBL328992 | 0.87 | MPI (0.63) | MPIPGK1PGK2PGDLPAR1 | |
| SCHEMBL1395698 | 0.87 | MPI (0.63) | MPIPGK1PGK2PGDLPAR1 | |
| SCHEMBL28125367 | 0.87 | MPI (0.63) | MPIPGK1PGK2PGDLPAR1 | |
| SCHEMBL10709491 | 0.87 | MPI (0.63) | MPIPGK1PGK2PGDLPAR1 | |
| SCHEMBL34088 | 0.87 | MPI (0.63) | MPIPGK1PGK2PGDLPAR1 | |
| Pyruvate SCHEMBL1409133 | 0.86 | MPI (0.50) | MPIPGK1PGK2PGDLPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130288313-A1 | Method of Producing L-Amino Acid | AJINOMOTO CO., INC. (JP) | 2013-10-31 | — | — | US | disclosed |
| US-8512987-B2 | culturing an Escherichia coli modified to increase the glycerol dehydrogenase and dihydroxyacetone kinase activities; useful as additives in animal feeds, health food, amino acid infusions | AJINOMOTO CO., INC. (JP) | 2013-08-20 | — | — | US | disclosed |
| US-20120040415-A1 | METHOD FOR PRODUCING AN L-AMINO ACID | AJINOMOTO CO., INC. (JP) | 2012-02-16 | — | — | US | disclosed |
| US-20100047878-A1 | METHOD OF PRODUCING L-AMINO ACID | AJINOMOTO CO., INC. (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2113570-A1 | METHOD OF PRODUCING L-AMINO ACID | Ajinomoto Co., Inc. (JP) | 2009-11-04 | — | — | EP | disclosed |