Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.74 |
| ▸ | PARP1 | P09874 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | PHGDH | O43175 | 3/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | RRM1 | P23921 | 1/20 | 0.62 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17107249 | 0.97 | SCD (0.78) | SCDPARP1LMNAALDH1A1PHGDH | |
| SCHEMBL17107123 | 0.95 | LMNA (0.76) | SCDPARP1LMNAALDH1A1PHGDH | |
| SCHEMBL23674562 | 0.93 | SCD (0.84) | SCDPARP1LMNAALDH1A1PHGDH | |
| SCHEMBL1270375 | 0.88 | SCD (0.89) | SCDPARP1LMNAALDH1A1PHGDH | |
| SCHEMBL3341958 | 0.88 | MAPT (0.79) | SCDLMNAALDH1A1MAPTKDM4E | |
| SCHEMBL14102514 | 0.87 | KMT2A (0.67) | SCDLMNAALDH1A1MAPTKDM4E | |
| SCHEMBL6249035 | 0.87 | SCD (0.74) | SCDPARP1LMNAALDH1A1PHGDH | |
| SCHEMBL13206963 | 0.87 | SCD (0.82) | SCDPARP1LMNAPHGDHADORA3 | |
| SCHEMBL16562127 | 0.85 | SCD (1.00) | SCDPARP1LMNAALDH1A1PHGDH | |
| SCHEMBL4746841 | 0.85 | ALDH1A1 (0.63) | SCDPARP1LMNAALDH1A1PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2005-03-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | PTPRS, PTPRJ, PTPRCAP | SCD 3999/4885PARP1 4726/4885LMNA 4884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.