Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 15/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157833 | 1.00 | TBXAS1 (0.56) | TBXAS1ESR1CA12CA1CA2 | |
| SCHEMBL6879547 | 1.00 | TBXAS1 (0.56) | TBXAS1ESR1CA12CA1CA2 | |
| SCHEMBL6156377 | 0.91 | CA12 (0.49) | TBXAS1ESR1CA12CA1CA2 | |
| SCHEMBL6154738 | 0.91 | CA12 (0.49) | TBXAS1ESR1CA12CA1CA2 | |
| SCHEMBL6154731 | 0.91 | CA12 (0.49) | TBXAS1ESR1CA12CA1CA2 | |
| SCHEMBL6883261 | 0.82 | TBXAS1 (0.46) | TBXAS1CA12CA1CA2CA6 | |
| SCHEMBL6883259 | 0.82 | TBXAS1 (0.46) | TBXAS1CA12CA1CA2CA6 | |
| SCHEMBL10360885 | 0.81 | ESR1 (0.39) | TBXAS1ESR1CA12CA1CA2 | |
| SCHEMBL10360886 | 0.81 | ESR1 (0.39) | TBXAS1ESR1CA12CA1CA2 | |
| SCHEMBL6881468 | 0.78 | AKT1 (0.47) | TBXAS1CA12CA1CA2CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |