Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6883261 | 1.00 | TBXAS1 (0.46) | TBXAS1NR1I2PGRADORA3PTGS2 | |
| SCHEMBL6157833 | 0.82 | TBXAS1 (0.56) | TBXAS1ALDH1A1KDM4ECA12CA1 | |
| SCHEMBL6879547 | 0.82 | TBXAS1 (0.56) | TBXAS1ALDH1A1KDM4ECA12CA1 | |
| SCHEMBL6157831 | 0.82 | TBXAS1 (0.56) | TBXAS1ALDH1A1KDM4ECA12CA1 | |
| SCHEMBL10360885 | 0.79 | ESR1 (0.39) | TBXAS1ALDH1A1KDM4ECA12CA1 | |
| SCHEMBL10360886 | 0.79 | ESR1 (0.39) | TBXAS1ALDH1A1KDM4ECA12CA1 | |
| SCHEMBL6881468 | 0.79 | AKT1 (0.47) | TBXAS1ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL6881472 | 0.79 | AKT1 (0.47) | TBXAS1ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL6154731 | 0.76 | CA12 (0.49) | TBXAS1ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL6154738 | 0.76 | CA12 (0.49) | TBXAS1ALDH1A1KDM4ESMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |