Acetone

Acetone

SCHEMBL6157864

CC(C)=O.CC(C)=O.CC(C)=O.N.OCCO

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.55
TSHR P16473 3/20 0.46
ALDH1A1 P00352 5/20 0.40
TDP1 Q9NUW8 3/20 0.40
FFAR3 O14843 2/20 0.39
THPO P40225 1/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
TRPA1 O75762 1/20 0.38
CA1 P00915 2/20 0.36
ALOX15 P16050 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
SLC15A2 Q16348 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CAMK2A Q9UQM7 1/20 0.32
KDM4E B2RXH2 1/20 0.31
CA2 P00918 1/20 0.31
PTGS1 P23219 1/20 0.31
MMP12 P39900 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL4650155 0.95 LMNA (0.60) LMNATSHRALDH1A1TDP1FFAR3
Acetone SCHEMBL3726673 0.95 LMNA (0.60) LMNATSHRALDH1A1TDP1FFAR3
Acetone SCHEMBL689569 0.95
Acetic Acid SCHEMBL29226934 0.87
Acetic Acid SCHEMBL4168552 0.87 FFAR3 (0.58) LMNATSHRALDH1A1TDP1FFAR3
Acetone SCHEMBL9651624 0.87 LMNA (0.50) LMNATSHRALDH1A1TDP1FFAR3
Acetone SCHEMBL9719637 0.84 LMNA (0.46) LMNATSHRALDH1A1TDP1FFAR3
Acetic Acid SCHEMBL1578192 0.82 FFAR3 (0.64) LMNATSHRALDH1A1TDP1FFAR3
Butanedione SCHEMBL1925936 0.82 TSHR (0.64) LMNATSHRALDH1A1TDP1FFAR3
Acetic Acid SCHEMBL7784606 0.82 FFAR3 (0.64) LMNATSHRALDH1A1TDP1FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050028956-A1 Method for making tissue product containing carboxylated cellulosic fibers WEYERHAEUSER COMPANY 2005-02-10 US disclosed
US-20050028955-A1 Tissue product containing carboxylated cellulosic fibers WEYERHAEUSER COMPANY 2005-02-10 US disclosed
EP-1505208-A2 Method for making tissue product containing carboxylated cellulosic fibers Weyerhaeuser Company (US) 2005-02-09 EP disclosed
EP-1505207-A2 Tissue product containing carboxylated cellulosic fibers Weyerhaeuser Company (US) 2005-02-09 EP disclosed