Acetone

Acetone

SCHEMBL9719637

CC(C)=O.CC(C)=O.CC(C)=O.COC.OCCO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.46
ALDH1A1 P00352 6/20 0.44
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
TSHR P16473 6/20 0.39
TDP1 Q9NUW8 1/20 0.35
HSD17B10 Q99714 2/20 0.35
TRPA1 O75762 1/20 0.33
THPO P40225 1/20 0.33
FFAR3 O14843 1/20 0.33
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33
CA1 P00915 1/20 0.31
ALOX15 P16050 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL15334117 0.89 FFAR3 (0.50) LMNAALDH1A1MGAMGAASI
Acetic Acid SCHEMBL79590 0.89 FFAR3 (0.50) LMNAALDH1A1MGAMGAASI
Acetone SCHEMBL3726673 0.88 LMNA (0.60) LMNAALDH1A1TSHRTDP1HSD17B10
Acetone SCHEMBL689569 0.88
Acetone SCHEMBL4650155 0.88 LMNA (0.60) LMNAALDH1A1TSHRTDP1HSD17B10
Acetamide SCHEMBL16030762 0.86 LMNA (0.53) LMNAALDH1A1MGAMGAASI
Acetone SCHEMBL29135357 0.85 ALDH1A1 (0.46) LMNAALDH1A1MGAMGAASI
Acetone SCHEMBL6157864 0.84 LMNA (0.55) LMNAALDH1A1TSHRTDP1HSD17B10
Ethylene Glycol SCHEMBL15995529 0.83 TSHR (0.56) ALDH1A1TSHR
Acetone SCHEMBL8840751 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5104575-A Using a porous polymer support modified by a phenolic or thiophenolic compound and calcium oxide or hydroxide/activator complex UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1992-04-14 US disclosed
US-4902658-A Alkoxylation using heterogeneous calcium catalysts and products therefrom UNION CARBIDE CORPORATION (US) 1990-02-20 US disclosed