Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085195 | 0.83 | P2RX7 (0.39) | P2RX7 | |
| SCHEMBL6162431 | 0.81 | P2RX7 (0.35) | P2RX7HSD11B1 | |
| SCHEMBL6162070 | 0.80 | — | — | |
| SCHEMBL6159838 | 0.79 | PPARG (0.39) | P2RX7 | |
| SCHEMBL6160714 | 0.78 | — | — | |
| SCHEMBL6161085 | 0.78 | — | — | |
| SCHEMBL6158527 | 0.77 | PPARG (0.39) | P2RX7 | |
| SCHEMBL7680113 | 0.74 | EPHX2 (0.36) | EPHX2 | |
| SCHEMBL7680109 | 0.74 | EPHX2 (0.36) | EPHX2 | |
| SCHEMBL6158526 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178969-B1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2005-07-13 | — | — | EP | disclosed |
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |