Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.62 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.62 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | XIAP | P98170 | 1/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KYNU | Q16719 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5286288 | 1.00 | GRM2 (0.62) | GRM2GRM3SLC1A1SLC1A2SLC1A3 | |
| SCHEMBL6158397 | 0.89 | GRM2 (0.59) | GRM2GRM3SLC1A1SLC1A2SLC1A3 | |
| SCHEMBL8558695 | 0.87 | GRM2 (0.57) | GRM2GRM3SLC1A1SLC1A2SLC1A3 | |
| SCHEMBL28640680 | 0.86 | CYP2C19 (0.53) | GRM2GRM3ALPIPKMPTGS1 | |
| SCHEMBL7973743 | 0.85 | CYP2C19 (0.61) | GRM2GRM3CYP2C19EPHX1CYP2D6 | |
| SCHEMBL5282418 | 0.83 | GRM2 (0.79) | GRM2GRM3SLC1A1SLC1A2SLC1A3 | |
| SCHEMBL29182085 | 0.81 | MMP8 (0.48) | GRM2GRM3CYP2C19 | |
| SCHEMBL10150939 | 0.81 | CYP2C19 (0.57) | GRM2GRM3CYP2C19EPHX1CYP2D6 | |
| SCHEMBL9065063 | 0.80 | KYNU (0.70) | GRM2GRM3SLC1A1SLC1A2SLC1A3 | |
| SCHEMBL9065025 | 0.80 | KYNU (0.70) | GRM2GRM3SLC1A1SLC1A2SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118178053-A | Degradable bone scaffold with piezoelectric effect and preparation method thereof | 佛山科学技术学院 | 2024-06-14 | — | — | CN | claimed |
| CN-118178053-A | Degradable bone scaffold with piezoelectric effect and preparation method thereof | 佛山科学技术学院 | 2024-06-14 | — | — | CN | disclosed |
| US-20050256095-A1 | Asthma and colitis treatment methods | BIOVIE INC. | 2005-11-17 | — | — | US | disclosed |
| CN-1109032-C | Compounds analogous to thalidomide from class comprising piperidine-2,6-diones | GRUENENTHAL GMBH (DE) | 2003-05-21 | — | — | CN | disclosed |
| US-6110941-A | AN IMMUNOMODULATOR MODULATING THE IMMUNE RESPONSE OF A MAMMAL, INHIBITING ANTIGEN-INDUCED SYNTHESIS OF INTERLEUKIN-2 | GRUENENTHAL GMBH (DE) | 2000-08-29 | — | — | US | disclosed |
| CN-1190096-A | Compounds analogous to thalidomide from class comprising piperidine-2,6-diones | GRUENENTHAL GMBH (DE) | 1998-08-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256095-A1 | Asthma and colitis treatment methods | HSD3B1, HSD17B1, HSD11B1 | GRM2 2799/4885GRM3 823/4885SLC1A1 4693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.