Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 10/20 | 0.76 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.60 |
| ▸ | PI4KA | P42356 | 2/20 | 0.59 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.59 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.59 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291896 | 0.81 | FDPS (0.52) | AHCY | |
| SCHEMBL2561529 | 0.81 | AHCY (0.66) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL15577353 | 0.81 | AHCY (0.70) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL1798270 | 0.81 | ADORA2A (0.72) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL1020380 | 0.80 | AHCY (1.00) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL1733018 | 0.78 | AHCY (0.66) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL1733016 | 0.78 | AHCY (0.66) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL11378379 | 0.78 | AHCY (0.66) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL1871838 | 0.78 | ADORA2A (0.75) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL11222112 | 0.78 | ADORA2A (0.80) | ADORA2AADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206459-B1 | 9-(PHOSPHONYLMETHOXYALKYL) ADENINES, METHOD FOR THEIR PREPARATION AND THEIR USE | Ceskoslovenska akademie ved (CS) | 1992-07-15 | — | — | EP | claimed |
| EP-0206459-A2 | 9-(Phosphonylmethoxyalkyl) adenines, method for their preparation and their use | Ceskoslovenska akademie ved (CS) | 1986-12-30 | — | — | EP | claimed |
| EP-1243590-B1 | Nucleotide analog composition and synthesis method | GILEAD SCIENCES INC (US) | 2005-02-09 | — | — | EP | disclosed |
| EP-0206459-B1 | 9-(PHOSPHONYLMETHOXYALKYL) ADENINES, METHOD FOR THEIR PREPARATION AND THEIR USE | Ceskoslovenska akademie ved (CS) | 1992-07-15 | — | — | EP | disclosed |
| EP-0205826-B1 | PHOSPHONYLMETHOXYALKYL ADENINES FOR THE TREATMENT OF VIRUS DISEASES | Stichting REGA V.Z.W. (BE) | 1992-03-18 | — | — | EP | disclosed |
| US-4808716-A | VIRICIDES OR CHEMICAL INTERMEDIATES | CESKOSLOVENSKA AKADEMIC VED (CS) | 1989-02-28 | — | — | US | disclosed |
| US-4724233-A | VIRICIDES | STICHTING REGA VZW (BE) | 1988-02-09 | — | — | US | disclosed |
| EP-0206459-A2 | 9-(Phosphonylmethoxyalkyl) adenines, method for their preparation and their use | Ceskoslovenska akademie ved (CS) | 1986-12-30 | — | — | EP | disclosed |
| EP-0205826-A2 | Phosphonylmethoxyalkyl adenines for the treatment of virus diseases | Stichting REGA V.Z.W. (BE) | 1986-12-30 | — | — | EP | disclosed |